Research Article

NLRP3 Susceptible Gene Polymorphisms in Patients with Primary Gouty Arthritis and Hyperuricemia

Table 6

Haplotypes of the NLRP3 gene with the risk of HUA.

HaplotypesControl frequencyCase frequencyOR (95% CI) value

rs10754558/rs35829419/rs3738448/rs3806268/rs7525979
GCGAC0.31430.26871.00—
CCGAC0.22640.26071.60 (1.16-2.22)0.0046
CCGGC0.18910.17910.94 (0.70-1.25)0.66
CCTGT0.10620.10661.21 (0.84-1.76)0.31
GCTGT0.08660.10161.30 (0.86-1.97)0.22
GCGGC0.06950.0781.31 (0.79-2.17)0.29

OR (95% CI) and values were obtained from logistic regression analysis.