Pioglitazone Mediates Cardiac Progenitor Formation through Increasing ROS Levels

Figure 4

Percentage of fluorescence and gene expression in treatment with pioglitazone in combination with two types of antioxidants. (a) Illustrated protocol of mESCs to progenitors treated in different concentrations of a-lipoic acid and CoQ10, on the day7. (b) Fluorescent imaging and intensities (c) of beating bodies after differentiation of EBs treated in different concentrations of a-lipoic acid along with Pio, on day 7. (d) Fluorescent imaging and intensities (e) of beating bodies after differentiation of EBs treated in different concentrations of CoQ10 along with Pio, on day 7. Scale bar is 200 mm.

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