Transforming Growth Factor Beta Receptor 2 (TGFBR2) Promoter Region Polymorphisms May Be Involved in Mandibular Retrognathism

Table 3

Genotype distribution among group and values.

Gene	rs	Genotype distribution and allele distributions, (%)			value^Genotype	value^Allele	value^Recessive
		Genotype	Orthognathic mandible	Mandibular retrognathism
TGFB1	rs1800469	TT	5 (10.0)	4 (4.4)	0.310	0.525	0.199
		CT	18 (36.0)	41 (45.6)
		CC	27 (54.0)	45 (50.0)
		A	28 (28.0)	49 (27.2)
		G	72 (72.0)	131 (72.8)
	rs4803455	CC	10 (20.8)	18 (21.4)	0.740	0.692	0.478
		CA	27 (56.3)	42 (50.0)
		AA	11 (22.9)	24 (28.6)
		C	47 (48.0)	78 (46.4)
		A	49 (52.0)	90 (57.3)
TGFBR2	rs3087465	AA	6 (12.0)	3 (3.3)	0.098	0.603	0.045
		AG	21 (42.0)	48 (53.3)
		GG	23 (46.0)	39 (43.3)
		A	33 (33.0)	54 (30.0)
		G	67 (67.0)	126 (70.0)
	rs764522	GG	0 (0.0)	2 (2.3)	0.575	0.525	0.302
		GC	11 (23.9)	22 (25.0)
		CC	35 (76.1)	64 (72.7)
		G	11 (12.0)	26 (14.8)
		C	81 (88.0)	150 (85.2)

Note: means statistically significant difference; : number of individuals; %: percent; rs: the code of polymorphisms; TGFB1: transforming growth factor beta 1; TGFBR2: transforming growth factor beta receptor 2; C: cytosine; A: adenine; T: thymine; G: guanine.