Low-Temperature Plasma Short Exposure to Decontaminate Peri-Implantitis-Related Multispecies Biofilms on Titanium Surfaces In Vitro

Table 5

Comparisons against LPT groups.

Bacteria	Biofilm	Comparison		Group 2	value	Result	95% CI
A. naeslundii	24 h	No treatment	vs.	Plasma 1 min/3 mm	0.014		4.38 (3.12, 4.70)
		No treatment	vs.	Plasma 1 min/10 mm	0.015		4.38 (2.23, 4.70)
		No treatment	vs.	Plasma 3 min/3 mm	0.015		4.38 (3.06, 4.70)
		No treatment	vs.	Plasma 3 min/10 mm	0.015		4.38 (2.47, 4.70)
		No treatment	vs.	Plasma 5 min/3 mm	0.014		4.38 (2.75, 4.70)
		No treatment	vs.	Plasma 5 min/10 mm	0.014		4.38 (3.58, 4.70)
		Chlorhexidine	vs.	Plasma 1 min/3 mm	0.156	Chlorhexidine & plasma 1 min/3 mm n.s.	1.32 (0.00, 1.91)
		Chlorhexidine	vs.	Plasma 1 min/10 mm	0.561	Chlorhexidine & plasma 1 min/10 mm n.s.	0.35 (-0.88, 1.91)
		Chlorhexidine	vs.	Plasma 3 min/3 mm	0.217	Chlorhexidine & plasma 3 min/3 mm n.s.	0.95 (0.00, 1.91)
		Chlorhexidine	vs.	Plasma 3 min/10 mm	0.507	Chlorhexidine & plasma 3 min/10 mm n.s.	0.38 (-0.83, 1.91)
		Chlorhexidine	vs.	Plasma 5 min/3 mm	0.207	Chlorhexidine & plasma 5 min/3 mm n.s.	1.32 (0.00, 1.91)
		Chlorhexidine	vs.	Plasma 5 min/10 mm	0.115	Chlorhexidine & plasma 5 min/10 mm n.s.	1.32 (0.00, 1.91)
		Amoxicillin	vs.	Plasma 1 min/3 mm	0.014		2.60 (2.30, 3.53)
		Amoxicillin	vs.	Plasma 1 min/10 mm	0.016		2.30 (0.40, 3.53)
		Amoxicillin	vs.	Plasma 3 min/3 mm	0.015		2.45 (1.28, 3.53)
		Amoxicillin	vs.	Plasma 3 min/10 mm	0.016		2.30 (0.45, 3.53)
		Amoxicillin	vs.	Plasma 5 min/3 mm	0.014	Amoxicillin > plasma 5 min/3 mm	2.60 (2.00, 3.53)
		Amoxicillin	vs.	Plasma 5 min/10 mm	0.014		2.60 (2.30, 3.53)
		Metronidazole	vs.	Plasma 1 min/3 mm	0.277	Metronidazole & plasma 1 min/3 mm n.s.	0.00 (0.00, 2.08)
		Metronidazole	vs.	Plasma 1 min/10 mm	0.794	Metronidazole & plasma 1 min/10 mm n.s.	0.00 (-0.88, 2.08)
		Metronidazole	vs.	Plasma 3 min/3 mm	0.435	Metronidazole & plasma 3 min/3 mm n.s.	0.00 (0.00, 2.08)
		Metronidazole	vs.	Plasma 3 min/10 mm	0.664	Metronidazole & plasma 3 min/10 mm n.s.	0.00 (-0.83, 2.08)
		Metronidazole	vs.	Plasma 5 min/3 mm	0.361	Metronidazole & plasma 5 min/3 mm n.s.	0.00 (0.00, 2.08)
		Metronidazole	vs.	Plasma 5 min/10 mm	0.240	Metronidazole & plasma 5 min/10 mm n.s.	0.00 (0.00, 2.08)
		Amoxicillin+metronidazole	vs.	Plasma 1 min/3 mm	0.101	Amoxicillin+metronidazole & plasma 1 min/3 mm n.s.	1.79 (0.00, 2.08)
		Amoxicillin+metronidazole	vs.	Plasma 1 min/10 mm	0.618	Amoxicillin+metronidazole & Plasma 1 min/10 mm n.s.	0.00 (-0.36, 2.08)
		Amoxicillin+metronidazole	vs.	Plasma 3 min/3 mm	0.132	Amoxicillin+metronidazole & plasma 3 min/3 mm n.s.	0.82 (0.00, 2.08)
		Amoxicillin+metronidazole	vs.	Plasma 3 min/10 mm	0.410	Amoxicillin+metronidazole & plasma 3 min/10 mm n.s.	0.12 (-0.24, 2.08)
		Amoxicillin+metronidazole	vs.	Plasma 5 min/3 mm	0.208	Amoxicillin+metronidazole & plasma 5 min/3 mm n.s.	1.79 (0.00, 2.08)
		Amoxicillin+metronidazole	vs.	Plasma 5 min/10 mm	0.088	Amoxicillin+metronidazole & plasma 5 min/10 mm n.s.	1.79 (0.00, 2.08)
	3 d	No treatment	vs.	Plasma 1 min/3 mm	0.016		3.49 (2.30, 4.34)
		No treatment	vs.	Plasma 1 min/10 mm	0.017		3.34 (1.99, 4.34)
		No treatment	vs.	Plasma 3 min/3 mm	0.012		4.25 (3.60, 4.70)
		No treatment	vs.	Plasma 3 min/10 mm	0.016		3.93 (2.39, 4.34)
		No treatment	vs.	Plasma 5 min/3 mm	0.012		4.25 (3.60, 4.70)
		No treatment	vs.	Plasma 5 min/10 mm	0.012		4.25 (3.60, 4.70)
		Chlorhexidine	vs.	Plasma 1 min/3 mm	0.238	n.s.	1.08 (-1.32, 2.64)
		Chlorhexidine	vs.	Plasma 1 min/10 mm	0.340	n.s.	0.65 (-1.61, 2.64)
		Chlorhexidine	vs.	Plasma 3 min/3 mm	0.051	Chlorhexidine & plasma 3 min/3 mm n.s.	2.11 (0.00, 2.64)
		Chlorhexidine	vs.	Plasma 3 min/10 mm	0.174	Chlorhexidine & plasma 3 min/10 mm n.s.	1.30 (0.00, 2.64)
		Chlorhexidine	vs.	Plasma 5 min/3 mm	0.051	Chlorhexidine & plasma 5 min/3 mm n.s.	2.11 (0.00, 2.64)
		Chlorhexidine	vs.	Plasma 5 min/10 mm	0.051	Chlorhexidine & plasma 5 min/10 mm n.s.	2.11 (0.00, 2.64)
		Amoxicillin	vs.	Plasma 1 min/3 mm	0.016		2.76 (1.77, 3.72)
		Amoxicillin	vs.	Plasma 1 min/10 mm	0.017		2.62 (1.39, 3.72)
		Amoxicillin	vs.	Plasma 3 min/3 mm	0.012		3.69 (3.00, 3.85)
		Amoxicillin	vs.	Plasma 3 min/10 mm	0.016		3.48 (1.79, 3.72)
		Amoxicillin	vs.	Plasma 5 min/3 mm	0.012		3.69 (3.00, 3.85)
		Amoxicillin	vs.	Plasma 5 min/10 mm	0.012		3.69 (3.00, 3.85)
		Metronidazole	vs.	Plasma 1 min/3 mm	0.016		2.58 (1.47, 3.75)
		Metronidazole	vs.	Plasma 1 min/10 mm	0.016		2.43 (1.09, 3.75)
		Metronidazole	vs.	Plasma 3 min/3 mm	0.012		3.62 (2.70, 3.78)
		Metronidazole	vs.	Plasma 3 min/10 mm	0.016		2.79 (1.71, 3.75)
		Metronidazole	vs.	Plasma 5 min/3 mm	0.012		3.62 (2.70, 3.78)
		Metronidazole	vs.	Plasma 5 min/10 mm	0.012		3.62 (2.70, 3.78)
		Amoxicillin+metronidazole	vs.	Plasma 1 min/3 mm	0.016	1 min	2.59 (1.39, 3.70)
		Amoxicillin+metronidazole	vs.	Plasma 1 min/10 mm	0.016	1 min	2.44 (1.00, 3.70)
		Amoxicillin+metronidazole	vs.	Plasma 3 min/3 mm	0.012	3 min	3.50 (2.70, 3.79)
		Amoxicillin+metronidazole	vs.	Plasma 3 min/10 mm	0.016	3 min	2.72 (1.39, 3.70)
		Amoxicillin+metronidazole	vs.	Plasma 5 min/3 mm	0.012		3.50 (2.70, 3.79)
		Amoxicillin+metronidazole	vs.	Plasma 5 min/10 mm	0.012	5 min	3.50 (2.70, 3.79)
	7 d	No treatment	vs.	Plasma 1 min/3 mm	0.012		4.12 (3.53, 4.89)
		No treatment	vs.	Plasma 1 min/10 mm	0.016		3.99 (2.62, 4.38)
		No treatment	vs.	Plasma 3 min/3 mm	0.012		4.12 (3.53, 4.89)
		No treatment	vs.	Plasma 3 min/10 mm	0.016		3.99 (2.62, 4.38)
No treatment		vs.	Plasma 5 min/3 mm	0.014	No treatment > plasma 5 min/3 mm	4.00 (3.53, 4.38)
No treatment		vs.	Plasma 5 min/10 mm	0.012		4.12 (3.53, 4.89)
Chlorhexidine		vs.	Plasma 1 min/3 mm	0.051	Chlorhexidine & plasma 1 min/3 mm n.s.	2.05 (0.00, 2.92)
Chlorhexidine		vs.	Plasma 1 min/10 mm	0.198	Chlorhexidine & plasma 1 min/10 mm n.s.	1.32 (0.00, 2.92)
Chlorhexidine		vs.	Plasma 3 min/3 mm	0.051	Chlorhexidine & plasma 3 min/3 mm n.s.	2.05 (0.00, 2.92)
Chlorhexidine		vs.	Plasma 3 min/10 mm	0.198	Chlorhexidine & plasma 3 min/10 mm n.s.	1.32 (0.00, 2.92)
Chlorhexidine		vs.	Plasma 5 min/3 mm	0.101	Chlorhexidine & plasma 5 min/3 mm n.s.	1.39 (0.00, 2.92)
Chlorhexidine		vs.	Plasma 5 min/10 mm	0.051	Chlorhexidine & plasma 5 min/10 mm n.s.	2.05 (0.00, 2.92)
Amoxicillin		vs.	Plasma 1 min/3 mm	0.012		2.80 (2.64, 3.48)
Amoxicillin		vs.	Plasma 1 min/10 mm	0.016		2.66 (1.32, 3.26)
Amoxicillin		vs.	Plasma 3 min/3 mm	0.012		2.80 (2.64, 3.48)
Amoxicillin		vs.	Plasma 3 min/10 mm	0.016		2.66 (1.32, 3.26)
Amoxicillin		vs.	Plasma 5 min/3 mm	0.014		2.68 (2.16, 3.26)
Amoxicillin		vs.	Plasma 5 min/10 mm	0.012		2.80 (2.64, 3.48)
Metronidazole		vs.	Plasma 1 min/3 mm	0.025		2.84 (2.08, 3.38)
Metronidazole		vs.	Plasma 1 min/10 mm	0.047		2.18 (0.00, 3.38)
Metronidazole		vs.	Plasma 3 min/3 mm	0.025		2.84 (2.08, 3.38)
Metronidazole		vs.	Plasma 3 min/10 mm	0.047		2.18 (0.00, 3.38)
Metronidazole		vs.	Plasma 5 min/3 mm	0.036		2.82 (0.00, 3.38)
Metronidazole		vs.	Plasma 5 min/10 mm	0.025		2.84 (2.08, 3.38)
Amoxicillin+metronidazole		vs.	Plasma 1 min/3 mm	0.012		2.81 (2.60, 3.88)
Amoxicillin+metronidazole		vs.	Plasma 1 min/10 mm	0.016		2.68 (1.30, 3.34)
Amoxicillin+metronidazole		vs.	Plasma 3 min/3 mm	0.012		2.81 (2.60, 3.88)
Amoxicillin+metronidazole		vs.	Plasma 3 min/10 mm	0.016		2.68 (1.30, 3.34)
Amoxicillin+metronidazole		vs.	Plasma 5 min/3 mm	0.014		2.70 (2.56, 3.34)
Amoxicillin+metronidazole		vs.	Plasma 5 min/10 mm	0.012		2.81 (2.60, 3.88)
P. gingivalis	24 h	No treatment	vs.	Plasma 1 min/3 mm	0.014		4.72 (3.81, 5.09)
		No treatment	vs.	Plasma 1 min/10 mm	0.016		4.60 (1.82, 5.09)
		No treatment	vs.	Plasma 3 min/3 mm	0.014		4.72 (3.52, 5.09)
		No treatment	vs.	Plasma 3 min/10 mm	0.016		4.60 (1.89, 5.09)
		No treatment	vs.	Plasma 5 min/3 mm	0.014		4.72 (3.13, 5.09)
		No treatment	vs.	Plasma 5 min/10 mm	0.012		4.84 (4.60, 5.13)
		Chlorhexidine	vs.	Plasma 1 min/3 mm	0.036		2.15 (0.00, 3.07)
		Chlorhexidine	vs.	Plasma 1 min/10 mm	0.210	Chlorhexidine & plasma 1 min/10 mm n.s.	1.79 (-0.63, 3.07)
		Chlorhexidine	vs.	Plasma 3 min/3 mm	0.036		2.15 (0.00, 3.07)
		Chlorhexidine	vs.	Plasma 3 min/10 mm	0.186	Chlorhexidine & plasma 3 min/10 mm n.s.	1.79 (-0.57, 3.07)
		Chlorhexidine	vs.	Plasma 5 min/3 mm	0.048		2.15 (0.00, 3.07)
		Chlorhexidine	vs.	Plasma 5 min/10 mm	0.025		2.46 (1.79, 3.07)
		Amoxicillin	vs.	Plasma 1 min/3 mm	0.014		3.45 (2.75, 3.98)
		Amoxicillin	vs.	Plasma 1 min/10 mm	0.021		3.38 (0.61, 3.98)
		Amoxicillin	vs.	Plasma 3 min/3 mm	0.014		3.45 (2.46, 3.98)
		Amoxicillin	vs.	Plasma 3 min/10 mm	0.021		3.38 (0.67, 3.98)
		Amoxicillin	vs.	Plasma 5 min/3 mm	0.014		3.45 (2.07, 3.98)
		Amoxicillin	vs.	Plasma 5 min/10 mm	0.012		3.66 (2.99, 4.07)
		Metronidazole	vs.	Plasma 1 min/3 mm	0.014		3.23 (2.91, 3.42)
		Metronidazole	vs.	Plasma 1 min/10 mm	0.016		3.18 (0.34, 3.42)
		Metronidazole	vs.	Plasma 3 min/3 mm	0.014		3.23 (2.62, 3.42)
		Metronidazole	vs.	Plasma 3 min/10 mm	0.016		3.18 (0.36, 3.42)
		Metronidazole	vs.	Plasma 5 min/3 mm	0.014		3.23 (2.23, 3.42)
		Metronidazole	vs.	Plasma 5 min/10 mm	0.012		3.30 (3.07, 4.23)
		Amoxicillin+metronidazole	vs.	Plasma 1 min/3 mm	0.014		3.47 (3.11, 4.26)
		Amoxicillin+metronidazole	vs.	Plasma 1 min/10 mm	0.016		3.28 (0.50, 4.26)
		Amoxicillin+metronidazole	vs.	Plasma 3 min/3 mm	0.014		3.47 (2.82, 4.26)
		Amoxicillin+metronidazole	vs.	Plasma 3 min/10 mm	0.016		3.28 (0.56, 4.26)
		Amoxicillin+metronidazole	vs.	Plasma 5 min/3 mm	0.014		3.47 (2.42, 4.26)
		Amoxicillin+metronidazole	vs.	Plasma 5 min/10 mm	0.012		3.67 (3.20, 4.43)
	3 d	No treatment	vs.	Plasma 1 min/3 mm	0.016		3.29 (2.16, 4.07)
		No treatment	vs.	Plasma 1 min/10 mm	0.017		2.46 (1.77, 3.93)
		No treatment	vs.	Plasma 3 min/3 mm	0.012		3.98 (3.78, 4.13)
		No treatment	vs.	Plasma 3 min/10 mm	0.016		3.29 (2.61, 4.07)
		No treatment	vs.	Plasma 5 min/3 mm	0.012		3.98 (3.78, 4.13)
		No treatment	vs.	Plasma 5 min/10 mm	0.012		3.98 (3.78, 4.13)
		Chlorhexidine	vs.	Plasma 1 min/3 mm	0.129	Chlorhexidine & plasma 1 min/3 mm n.s.	1.32 (0.00, 2.97)
		Chlorhexidine	vs.	Plasma 1 min/10 mm	0.392	Chlorhexidine & plasma 1 min/10 mm n.s.	0.68 (-1.32, 1.68)
		Chlorhexidine	vs.	Plasma 3 min/3 mm	0.025	Chlorhexidine > plasma 3 min/3 mm	2.07 (1.32, 2.97)
		Chlorhexidine	vs.	Plasma 3 min/10 mm	0.083	Chlorhexidine & plasma 3 min/10 mm n.s.	1.47 (0.00, 2.97)
		Chlorhexidine	vs.	Plasma 5 min/3 mm	0.025		2.07 (1.32, 2.97)
		Chlorhexidine	vs.	Plasma 5 min/10 mm	0.025		2.07 (1.32, 2.97)
		Amoxicillin	vs.	Plasma 1 min/3 mm	0.016		2.78 (1.51, 3.42)
		Amoxicillin	vs.	Plasma 1 min/10 mm	0.017		1.76 (1.07, 3.09)
		Amoxicillin	vs.	Plasma 3 min/3 mm	0.012		3.14 (2.86, 4.02)
		Amoxicillin	vs.	Plasma 3 min/10 mm	0.016		2.78 (1.76, 3.42)
		Amoxicillin	vs.	Plasma 5 min/3 mm	0.012		3.14 (2.86, 4.02)
		Amoxicillin	vs.	Plasma 5 min/10 mm	0.012		3.14 (2.86, 4.02)
		Metronidazole	vs.	Plasma 1 min/3 mm	0.016		2.48 (1.19, 3.58)
		Metronidazole	vs.	Plasma 1 min/10 mm	0.017		1.77 (0.87, 3.01)
		Metronidazole	vs.	Plasma 3 min/3 mm	0.012		3.30 (2.48, 3.85)
		Metronidazole	vs.	Plasma 3 min/10 mm	0.016		2.50 (1.69, 3.58)
		Metronidazole	vs.	Plasma 5 min/3 mm	0.012		3.30 (2.48, 3.85)
		Metronidazole	vs.	Plasma 5 min/10 mm	0.012		3.30 (2.48, 3.85)
		Amoxicillin+metronidazole	vs.	Plasma 1 min/3 mm	0.016		2.45 (1.28, 3.20)
		Amoxicillin+metronidazole	vs.	Plasma 1 min/10 mm	0.017		1.38 (0.82, 2.60)
		Amoxicillin+metronidazole	vs.	Plasma 3 min/3 mm	0.012		2.92 (2.60, 3.62)
		Amoxicillin+metronidazole	vs.	Plasma 3 min/10 mm	0.016		2.45 (1.28, 3.20)
		Amoxicillin+metronidazole	vs.	Plasma 5 min/3 mm	0.012		2.92 (2.60, 3.62)
		Amoxicillin+metronidazole	vs.	Plasma 5 min/10 mm	0.012		2.92 (2.60, 3.62)
	7 d	No treatment	vs.	Plasma 1 min/3 mm	0.012		3.96 (3.58, 4.28)
		No treatment	vs.	Plasma 1 min/10 mm	0.014	No treatment > plasma 1 min/10 mm	3.91 (2.96, 4.16)
		No treatment	vs.	Plasma 3 min/3 mm	0.014		3.91 (2.96, 4.16)
		No treatment	vs.	Plasma 3 min/10 mm	0.016		3.27 (2.08, 4.16)
No treatment		vs.	Plasma 5 min/3 mm	0.014		3.91 (2.96, 4.16)
No treatment		vs.	Plasma 5 min/10 mm	0.012	No treatment > plasma 5 min/10 mm	3.96 (3.58, 4.28)
Chlorhexidine		vs.	Plasma 1 min/3 mm	0.051	Chlorhexidine & plasma 1 min/3 mm n.s.	2.38 (0.00, 2.87)
Chlorhexidine		vs.	Plasma 1 min/10 mm	0.088	Chlorhexidine & plasma 1 min/10 mm n.s.	2.15 (0.00, 2.87)
Chlorhexidine		vs.	Plasma 3 min/3 mm	0.088	Chlorhexidine & plasma 3 min/3 mm n.s.	2.15 (0.00, 2.87)
Chlorhexidine		vs.	Plasma 3 min/10 mm	0.185	Chlorhexidine & plasma 3 min/10 mm n.s.	1.26 (-1.32, 2.87)
Chlorhexidine		vs.	Plasma 5 min/3 mm	0.088	Chlorhexidine & plasma 5 min/3 mm n.s.	2.15 (0.00, 2.87)
Chlorhexidine		vs.	Plasma 5 min/10 mm	0.051	Chlorhexidine & plasma 5 min/10 mm n.s.	2.38 (0.00, 2.87)
Amoxicillin		vs.	Plasma 1 min/3 mm	0.012		2.93 (2.30, 4.02)
Amoxicillin		vs.	Plasma 1 min/10 mm	0.014		2.78 (2.30, 3.89)
Amoxicillin		vs.	Plasma 3 min/3 mm	0.014		2.78 (2.30, 3.89)
Amoxicillin		vs.	Plasma 3 min/10 mm	0.016		2.53 (0.98, 3.89)
Amoxicillin		vs.	Plasma 5 min/3 mm	0.014		2.78 (2.30, 3.89)
Amoxicillin		vs.	Plasma 5 min/10 mm	0.012		2.93 (2.30, 4.02)
Metronidazole		vs.	Plasma 1 min/3 mm	0.012		3.03 (2.78, 3.81)
Metronidazole		vs.	Plasma 1 min/10 mm	0.014		2.88 (2.48, 3.66)
Metronidazole		vs.	Plasma 3 min/3 mm	0.014		2.88 (2.48, 3.66)
Metronidazole		vs.	Plasma 3 min/10 mm	0.016		2.63 (1.46, 3.66)
Metronidazole		vs.	Plasma 5 min/3 mm	0.014		2.88 (2.48, 3.66)
Metronidazole		vs.	Plasma 5 min/10 mm	0.012		3.03 (2.78, 3.81)
Amoxicillin+metronidazole		vs.	Plasma 1 min/3 mm	0.012		3.02 (2.30, 3.83)
Amoxicillin+metronidazole		vs.	Plasma 1 min/10 mm	0.014		2.98 (2.30, 3.76)
Amoxicillin+metronidazole		vs.	Plasma 3 min/3 mm	0.014		2.98 (2.30, 3.76)
Amoxicillin+metronidazole		vs.	Plasma 3 min/10 mm	0.016		2.30 (0.98, 3.76)
Amoxicillin+metronidazole		vs.	Plasma 5 min/3 mm	0.014		2.98 (2.30, 3.76)
Amoxicillin+metronidazole		vs.	Plasma 5 min/10 mm	0.012		3.02 (2.30, 3.83)
S. oralis	24 h	No treatment	vs.	Plasma 1 min/3 mm	0.012		4.63 (4.46, 4.94)
		No treatment	vs.	Plasma 1 min/10 mm	0.016		4.60 (1.85, 4.81)
		No treatment	vs.	Plasma 3 min/3 mm	0.012		4.63 (4.46, 4.94)
		No treatment	vs.	Plasma 3 min/10 mm	0.016		4.60 (2.20, 4.81)
		No treatment	vs.	Plasma 5 min/3 mm	0.014		4.60 (2.74, 4.81)
		No treatment	vs.	Plasma 5 min/10 mm	0.014		4.60 (3.33, 4.81)
		Chlorhexidine	vs.	Plasma 1 min/3 mm	0.102	Chlorhexidine & plasma 1 min/3 mm n.s.	0.66 (0.00, 3.42)
		Chlorhexidine	vs.	Plasma 1 min/10 mm	0.545	Chlorhexidine & plasma 1 min/10 mm n.s.	0.00 (-1.63, 3.42)
		Chlorhexidine	vs.	Plasma 3 min/3 mm	0.102	Chlorhexidine & plasma 3 min/3 mm n.s.	0.66 (0.00, 3.42)
		Chlorhexidine	vs.	Plasma 3 min/10 mm	0.545	Chlorhexidine & plasma 3 min/10 mm n.s.	0.00 (-1.28, 3.42)
		Chlorhexidine	vs.	Plasma 5 min/3 mm	0.277	Chlorhexidine & plasma 5 min/3 mm n.s.	0.00 (0.00, 3.42)
		Chlorhexidine	vs.	Plasma 5 min/10 mm	0.277	Chlorhexidine & plasma 5 min/10 mm n.s.	0.00 (0.00, 3.42)
		Amoxicillin	vs.	Plasma 1 min/3 mm	0.012		3.83 (2.62, 4.35)
		Amoxicillin	vs.	Plasma 1 min/10 mm	0.021		3.01 (1.15, 4.21)
		Amoxicillin	vs.	Plasma 3 min/3 mm	0.012		3.83 (2.62, 4.35)
		Amoxicillin	vs.	Plasma 3 min/10 mm	0.016		3.01 (1.00, 4.21)
		Amoxicillin	vs.	Plasma 5 min/3 mm	0.014		3.55 (2.14, 4.21)
		Amoxicillin	vs.	Plasma 5 min/10 mm	0.014		3.55 (2.62, 4.21)
		Metronidazole	vs.	Plasma 1 min/3 mm	0.012		3.24 (3.05, 4.26)
		Metronidazole	vs.	Plasma 1 min/10 mm	0.016		3.18 (0.45, 3.41)
		Metronidazole	vs.	Plasma 3 min/3 mm	0.012		3.24 (3.05, 4.26)
		Metronidazole	vs.	Plasma 3 min/10 mm	0.016		3.18 (0.81, 3.41)
		Metronidazole	vs.	Plasma 5 min/3 mm	0.014		3.22 (2.05, 3.41)
		Metronidazole	vs.	Plasma 5 min/10 mm	0.014		3.22 (2.65, 3.41)
		Amoxicillin+metronidazole	vs.	Plasma 1 min/3 mm	0.012		3.83 (3.20, 4.39)
		Amoxicillin+metronidazole	vs.	Plasma 1 min/10 mm	0.016		3.58 (0.93, 3.88)
		Amoxicillin+metronidazole	vs.	Plasma 3 min/3 mm	0.012		3.83 (3.20, 4.39)
		Amoxicillin+metronidazole	vs.	Plasma 3 min/10 mm	0.016		3.58 (1.24, 3.88)
		Amoxicillin+metronidazole	vs.	Plasma 5 min/3 mm	0.014		3.82 (2.18, 3.88)
		Amoxicillin+metronidazole	vs.	Plasma 5 min/10 mm	0.014		3.82 (2.77, 3.88)
	3 d	No treatment	vs.	Plasma 1 min/3 mm	0.012	No treatment > plasma 1 min/3 mm	3.95 (3.79, 4.48)
		No treatment	vs.	Plasma 1 min/10 mm	0.017		2.61 (1.71, 3.96)
		No treatment	vs.	Plasma 3 min/3 mm	0.012		3.95 (3.79, 4.48)
		No treatment	vs.	Plasma 3 min/10 mm	0.016		3.48 (2.10, 4.01)
		No treatment	vs.	Plasma 5 min/3 mm	0.012		3.95 (3.79, 4.48)
		No treatment	vs.	Plasma 5 min/10 mm	0.012		3.95 (3.79, 4.48)
		Chlorhexidine	vs.	Plasma 1 min/3 mm	0.025		2.26 (1.32, 2.99)
		Chlorhexidine	vs.	Plasma 1 min/10 mm	0.315	Chlorhexidine & plasma 1 min/10 mm n.s.	1.16 (-0.98, 2.90)
		Chlorhexidine	vs.	Plasma 3 min/3 mm	0.025		2.26 (1.32, 2.99)
		Chlorhexidine	vs.	Plasma 3 min/10 mm	0.129		1.46 (0.00, 2.99)
		Chlorhexidine	vs.	Plasma 5 min/3 mm	0.025		2.26 (1.32, 2.99)
		Chlorhexidine	vs.	Plasma 5 min/10 mm	0.025		2.26 (1.32, 2.99)
		Amoxicillin	vs.	Plasma 1 min/3 mm	0.012		3.42 (3.10, 3.92)
		Amoxicillin	vs.	Plasma 1 min/10 mm	0.017		2.03 (1.27, 3.42)
		Amoxicillin	vs.	Plasma 3 min/3 mm	0.012		3.42 (3.10, 3.92)
		Amoxicillin	vs.	Plasma 3 min/10 mm	0.016		2.85 (1.66, 3.57)
		Amoxicillin	vs.	Plasma 5 min/3 mm	0.012		3.42 (3.10, 3.92)
		Amoxicillin	vs.	Plasma 5 min/10 mm	0.012		3.42 (3.10, 3.92)
		Metronidazole	vs.	Plasma 1 min/3 mm	0.012		3.36 (2.48, 3.66)
		Metronidazole	vs.	Plasma 1 min/10 mm	0.017		1.95 (1.04, 3.37)
		Metronidazole	vs.	Plasma 3 min/3 mm	0.012		3.36 (2.48, 3.66)
		Metronidazole	vs.	Plasma 3 min/10 mm	0.016		2.41 (1.43, 3.64)
		Metronidazole	vs.	Plasma 5 min/3 mm	0.012		3.36 (2.48, 3.66)
		Metronidazole	vs.	Plasma 5 min/10 mm	0.012		3.36 (2.48, 3.66)
		Amoxicillin+metronidazole	vs.	Plasma 1 min/3 mm	0.012		3.31 (2.60, 4.34)
		Amoxicillin+metronidazole	vs.	Plasma 1 min/10 mm	0.017		2.02 (0.99, 3.49)
		Amoxicillin+metronidazole	vs.	Plasma 3 min/3 mm	0.012		3.31 (2.60, 4.34)
		Amoxicillin+metronidazole	vs.	Plasma 3 min/10 mm	0.016		2.60 (1.28, 3.62)
		Amoxicillin+metronidazole	vs.	Plasma 5 min/3 mm	0.012		3.31 (2.60, 4.34)
		Amoxicillin+metronidazole	vs.	Plasma 5 min/10 mm	0.012		3.31 (2.60, 4.34)
	7 d	No treatment	vs.	Plasma 1 min/3 mm	0.012		4.23 (3.32, 5.31)
		No treatment	vs.	Plasma 1 min/10 mm	0.014		3.95 (2.56, 4.67)
		No treatment	vs.	Plasma 3 min/3 mm	0.012		4.23 (3.32, 5.31)
		No treatment	vs.	Plasma 3 min/10 mm	0.014		3.95 (3.32, 4.67)
No treatment		vs.	Plasma 5 min/3 mm	0.012		4.23 (3.32, 5.31)
No treatment		vs.	Plasma 5 min/10 mm	0.012		4.23 (3.32, 5.31)
Chlorhexidine		vs.	Plasma 1 min/3 mm	0.203	Chlorhexidine & plasma 1 min/3 mm n.s.	0.00 (0.00, 3.31)
Chlorhexidine		vs.	Plasma 1 min/10 mm	0.477	Chlorhexidine & plasma 1 min/10 mm n.s.	0.00 (0.00, 3.31)
Chlorhexidine		vs.	Plasma 3 min/3 mm	0.203	Chlorhexidine & plasma 3 min/3 mm n.s.	0.00 (0.00, 3.31)
Chlorhexidine		vs.	Plasma 3 min/10 mm	0.477	Chlorhexidine & plasma 3 min/10 mm n.s.	0.00 (0.00, 3.31)
Chlorhexidine		vs.	Plasma 5 min/3 mm	0.203	Chlorhexidine & plasma 5 min/3 mm n.s.	0.00 (0.00, 3.31)
Chlorhexidine		vs.	Plasma 5 min/10 mm	0.203	Chlorhexidine & plasma 5 min/10 mm n.s.	0.00 (0.00, 3.31)
Amoxicillin		vs.	Plasma 1 min/3 mm	0.025		2.31 (1.91, 3.78)
Amoxicillin		vs.	Plasma 1 min/10 mm	0.087	Amoxicillin & plasma 1 min/10 mm n.s.	2.15 (0.00, 3.78)
Amoxicillin		vs.	Plasma 3 min/3 mm	0.025		2.31 (1.91, 3.78)
Amoxicillin		vs.	Plasma 3 min/10 mm	0.036		2.15 (0.00, 3.78)
Amoxicillin		vs.	Plasma 5 min/3 mm	0.025		2.31 (1.91, 3.78)
Amoxicillin		vs.	Plasma 5 min/10 mm	0.025		2.31 (1.91, 3.78)
Metronidazole		vs.	Plasma 1 min/3 mm	0.051	Metronidazole & plasma 1 min/3 mm n.s.	3.25 (0.00, 3.37)
Metronidazole		vs.	Plasma 1 min/10 mm	0.088	Metronidazole & plasma 1 min/10 mm n.s.	3.16 (0.00, 3.37)
Metronidazole		vs.	Plasma 3 min/3 mm	0.051	Metronidazole & plasma 3 min/3 mm n.s.	3.25 (0.00, 3.37)
Metronidazole		vs.	Plasma 3 min/10 mm	0.088	Metronidazole & plasma 3 min/10 mm n.s.	3.16 (0.00, 3.37)
Metronidazole		vs.	Plasma 5 min/3 mm	0.051	Metronidazole & plasma 5 min/3 mm n.s.	3.25 (0.00, 3.37)
Metronidazole		vs.	Plasma 5 min/10 mm	0.051	Metronidazole & plasma 5 min/10 mm n.s.	3.25 (0.00, 3.37)
Amoxicillin+metronidazole		vs.	Plasma 1 min/3 mm	0.025		2.64 (2.58, 3.51)
Amoxicillin+metronidazole		vs.	Plasma 1 min/10 mm	0.086		2.58 (0.00, 3.51)
Amoxicillin+metronidazole		vs.	Plasma 3 min/3 mm	0.025		2.64 (2.58, 3.51)
Amoxicillin+metronidazole		vs.	Plasma 3 min/10 mm	0.035		2.58 (0.00, 3.51)
Amoxicillin+metronidazole		vs.	Plasma 5 min/3 mm	0.025		2.64 (2.58, 3.51)
Amoxicillin+metronidazole		vs.	Plasma 5 min/10 mm	0.025		2.64 (2.58, 3.51)
V. dispar	24 h	No treatment	vs.	Plasma 1 min/3 mm	0.012		4.58 (4.00, 5.00)
		No treatment	vs.	Plasma 1 min/10 mm	0.016		4.32 (2.64, 4.85)
		No treatment	vs.	Plasma 3 min/3 mm	0.012		4.58 (4.00, 5.00)
		No treatment	vs.	Plasma 3 min/10 mm	0.016		4.32 (2.35, 4.85)
		No treatment	vs.	Plasma 5 min/3 mm	0.014		4.56 (3.68, 4.85)
		No treatment	vs.	Plasma 5 min/10 mm	0.012		4.58 (4.00, 5.00)
		Chlorhexidine	vs.	Plasma 1 min/3 mm	0.012		2.61 (2.21, 2.86)
		Chlorhexidine	vs.	Plasma 1 min/10 mm	0.018		2.26 (0.65, 2.68)
		Chlorhexidine	vs.	Plasma 3 min/3 mm	0.012		2.61 (2.21, 2.86)
		Chlorhexidine	vs.	Plasma 3 min/10 mm	0.018		2.26 (0.48, 2.68)
		Chlorhexidine	vs.	Plasma 5 min/3 mm	0.014		2.53 (1.54, 2.68)
		Chlorhexidine	vs.	Plasma 5 min/10 mm	0.012		2.61 (2.21, 2.86)
		Amoxicillin	vs.	Plasma 1 min/3 mm	0.012		2.53 (2.08, 4.56)
		Amoxicillin	vs.	Plasma 1 min/10 mm	0.021		2.38 (0.76, 3.75)
		Amoxicillin	vs.	Plasma 3 min/3 mm	0.012		2.53 (2.08, 4.56)
		Amoxicillin	vs.	Plasma 3 min/10 mm	0.021		2.33 (0.30, 3.75)
		Amoxicillin	vs.	Plasma 5 min/3 mm	0.014		2.42 (2.08, 3.75)
		Amoxicillin	vs.	Plasma 5 min/10 mm	0.012		2.53 (2.08, 4.56)
		Metronidazole	vs.	Plasma 1 min/3 mm	0.012		2.60 (2.30, 4.82)
		Metronidazole	vs.	Plasma 1 min/10 mm	0.016		2.48 (0.98, 3.72)
		Metronidazole	vs.	Plasma 3 min/3 mm	0.012		2.60 (2.30, 4.82)
		Metronidazole	vs.	Plasma 3 min/10 mm	0.016		2.48 (0.44, 3.72)
		Metronidazole	vs.	Plasma 5 min/3 mm	0.014		2.51 (2.30, 3.72)
		Metronidazole	vs.	Plasma 5 min/10 mm	0.012		2.60 (2.30, 4.82)
		Amoxicillin+metronidazole	vs.	Plasma 1 min/3 mm	0.012		2.58 (1.79, 4.06)
		Amoxicillin+metronidazole	vs.	Plasma 1 min/10 mm	0.021		2.38 (0.46, 3.93)
		Amoxicillin+metronidazole	vs.	Plasma 3 min/3 mm	0.012		2.58 (1.79, 4.06)
		Amoxicillin+metronidazole	vs.	Plasma 3 min/10 mm	0.028		2.26 (0.30, 3.93)
		Amoxicillin+metronidazole	vs.	Plasma 5 min/3 mm	0.014		2.51 (1.79, 3.93)
		Amoxicillin+metronidazole	vs.	Plasma 5 min/10 mm	0.012		2.58 (1.79, 4.06)
	3 d	No treatment	vs.	Plasma 1 min/3 mm	0.012		3.92 (3.15, 4.41)
		No treatment	vs.	Plasma 1 min/10 mm	0.017		2.97 (2.01, 4.02)
		No treatment	vs.	Plasma 3 min/3 mm	0.012		3.92 (3.15, 4.41)
		No treatment	vs.	Plasma 3 min/10 mm	0.016		3.79 (2.59, 4.02)
		No treatment	vs.	Plasma 5 min/3 mm	0.012		3.92 (3.15, 4.41)
		No treatment	vs.	Plasma 5 min/10 mm	0.012		3.92 (3.15, 4.41)
		Chlorhexidine	vs.	Plasma 1 min/3 mm	0.102	Chlorhexidine & plasma 1 min/3 mm n.s.	0.81 (0.00, 2.00)
		Chlorhexidine	vs.	Plasma 1 min/10 mm	0.802	Chlorhexidine & plasma 1 min/10 mm n.s.	0.00 (-1.79, 2.00)
		Chlorhexidine	vs.	Plasma 3 min/3 mm	0.102	Chlorhexidine & plasma 3 min/3 mm n.s.	0.81 (0.00, 2.00)
		Chlorhexidine	vs.	Plasma 3 min/10 mm	0.346	Chlorhexidine & plasma 3 min/10 mm n.s.	0.15 (0.00, 2.00)
		Chlorhexidine	vs.	Plasma 5 min/3 mm	0.102	Chlorhexidine & plasma 5 min/3 mm n.s.	0.81 (0.00, 2.00)
		Chlorhexidine	vs.	Plasma 5 min/10 mm	0.102	Chlorhexidine & plasma 5 min/10 mm n.s.	0.81 (0.00, 2.00)
		Amoxicillin	vs.	Plasma 1 min/3 mm	0.012		2.84 (2.15, 3.42)
		Amoxicillin	vs.	Plasma 1 min/10 mm	0.017		1.98 (0.54, 3.34)
		Amoxicillin	vs.	Plasma 3 min/3 mm	0.012		2.84 (2.15, 3.42)
		Amoxicillin	vs.	Plasma 3 min/10 mm	0.016		2.26 (1.28, 3.34)
		Amoxicillin	vs.	Plasma 5 min/3 mm	0.012		2.84 (2.15, 3.42)
		Amoxicillin	vs.	Plasma 5 min/10 mm	0.012		2.84 (2.15, 3.42)
		Metronidazole	vs.	Plasma 1 min/3 mm	0.012		2.57 (1.61, 2.89)
		Metronidazole	vs.	Plasma 1 min/10 mm	0.034		1.45 (0.22, 2.78)
		Metronidazole	vs.	Plasma 3 min/3 mm	0.012		2.57 (1.61, 2.89)
		Metronidazole	vs.	Plasma 3 min/10 mm	0.016		2.00 (1.13, 2.78)
		Metronidazole	vs.	Plasma 5 min/3 mm	0.012		2.57 (1.61, 2.89)
		Metronidazole	vs.	Plasma 5 min/10 mm	0.012		2.57 (1.61, 2.89)
		Amoxicillin+metronidazole	vs.	Plasma 1 min/3 mm	0.012		2.90 (2.38, 3.85)
		Amoxicillin+metronidazole	vs.	Plasma 1 min/10 mm	0.016		2.31 (0.77, 3.00)
		Amoxicillin+metronidazole	vs.	Plasma 3 min/3 mm	0.012		2.90 (2.38, 3.85)
		Amoxicillin+metronidazole	vs.	Plasma 3 min/10 mm	0.015		2.51 (1.58, 3.00)
		Amoxicillin+metronidazole	vs.	Plasma 5 min/3 mm	0.012		2.90 (2.38, 3.85)
		Amoxicillin+metronidazole	vs.	Plasma 5 min/10 mm	0.012		2.90 (2.38, 3.85)
	7 d	No treatment	vs.	Plasma 1 min/3 mm	0.012		3.89 (2.90, 4.81)
		No treatment	vs.	Plasma 1 min/10 mm	0.012		3.89 (2.90, 4.81)
		No treatment	vs.	Plasma 3 min/3 mm	0.012		3.89 (2.90, 4.81)
		No treatment	vs.	Plasma 3 min/10 mm	0.012		3.89 (2.90, 4.81)
No treatment		vs.	Plasma 5 min/3 mm	0.012		3.89 (2.90, 4.81)
No treatment		vs.	Plasma 5 min/10 mm	0.012		3.89 (2.90, 4.81)
Chlorhexidine		vs.	Plasma 1 min/3 mm	0.102	Chlorhexidine & plasma 1 min/3 mm n.s.	0.81 (0.00, 2.08)
Chlorhexidine		vs.	Plasma 1 min/10 mm	0.102	Chlorhexidine & plasma 1 min/10 mm n.s.	0.81 (0.00, 2.08)
Chlorhexidine		vs.	Plasma 3 min/3 mm	0.102	Chlorhexidine & plasma 3 min/3 mm n.s.	0.81 (0.00, 2.08)
Chlorhexidine		vs.	Plasma 3 min/10 mm	0.102	Chlorhexidine & plasma 3 min/10 mm n.s.	0.81 (0.00, 2.08)
Chlorhexidine		vs.	Plasma 5 min/3 mm	0.102	Chlorhexidine & plasma 5 min/3 mm n.s.	0.81 (0.00, 2.08)
Chlorhexidine		vs.	Plasma 5 min/10 mm	0.102	Chlorhexidine & plasma 5 min/10 mm n.s.	0.81 (0.00, 2.08)
Amoxicillin		vs.	Plasma 1 min/3 mm	0.025		2.54 (1.32, 3.01)
Amoxicillin		vs.	Plasma 1 min/10 mm	0.025		2.54 (1.32, 3.01)
Amoxicillin		vs.	Plasma 3 min/3 mm	0.025		2.54 (1.32, 3.01)
Amoxicillin		vs.	Plasma 3 min/10 mm	0.025		2.54 (1.32, 3.01)
Amoxicillin		vs.	Plasma 5 min/3 mm	0.025		2.54 (1.32, 3.01)
Amoxicillin		vs.	Plasma 5 min/10 mm	0.025		2.54 (1.32, 3.01)
Metronidazole		vs.	Plasma 1 min/3 mm	0.025		2.23 (1.91, 2.60)
Metronidazole		vs.	Plasma 1 min/10 mm	0.025		2.23 (1.91, 2.60)
Metronidazole		vs.	Plasma 3 min/3 mm	0.025		2.23 (1.91, 2.60)
Metronidazole		vs.	Plasma 3 min/10 mm	0.025		2.23 (1.91, 2.60)
Metronidazole		vs.	Plasma 5 min/3 mm	0.025		2.23 (1.91, 2.60)
Metronidazole		vs.	Plasma 5 min/10 mm	0.025		2.23 (1.91, 2.60)
Amoxicillin+metronidazole		vs.	Plasma 1 min/3 mm	0.025		2.38 (1.32, 2.64)
Amoxicillin+metronidazole		vs.	Plasma 1 min/10 mm	0.025		2.38 (1.32, 2.64)
Amoxicillin+metronidazole		vs.	Plasma 3 min/3 mm	0.025		2.38 (1.32, 2.64)
Amoxicillin+metronidazole		vs.	Plasma 3 min/10 mm	0.025		2.38 (1.32, 2.64)
Amoxicillin+metronidazole		vs.	Plasma 5 min/3 mm	0.025		2.38 (1.32, 2.64)
Amoxicillin+metronidazole		vs.	Plasma 5 min/10 mm	0.025		2.38 (1.32, 2.64)