Research Article
Anatomic Subsites and Prognosis of Gastric Signet Ring Cell Carcinoma: A SEER Population-Based 1 : 1 Propensity-Matched Study
Table 1
The characteristics of patients with GSRC according to tumor localization in the SEER database.
| | Characteristics | DGC | OGC | PGC | value | | 1084 | 351 | 604 |
| | Age (%) | 18-49 | 240 (22.1) | 75 (21.4) | 91 (15.1) | <0.001 | | 50-59 | 249 (23.0) | 93 (26.5) | 149 (24.7) | | 60-69 | 242 (22.3) | 90 (25.6) | 188 (31.1) | | 70-79 | 218 (20.1) | 59 (16.8) | 124 (20.5) | | ≥80 | 135 (12.5) | 34 (9.7) | 52 (8.6) | | Race (%) | White | 691 (63.7) | 255 (72.6) | 495 (82.0) | <0.001 | | Black | 155 (14.3) | 44 (12.5) | 40 (6.6) | | API | 232 (21.4) | 49 (14.0) | 64 (10.6) | | AI | 6 (0.6) | 3 (0.9) | 5 (0.8) | | Gender (%) | Male | 508 (46.9) | 175 (49.9) | 430 (71.2) | <0.001 | | Female | 576 (53.1) | 176 (50.1) | 174 (28.8) | | Marital status (%) | Divorced | 99 (9.1) | 45 (12.8) | 69 (11.4) | 0.009 | | Married | 646 (59.6) | 212 (60.4) | 367 (60.8) | | Widowed | 147 (13.6) | 38 (10.8) | 48 (7.9) | | Single | 192 (17.7) | 56 (16.0) | 120 (19.9) | | Median household income (%) | Quartile 1 | 268 (24.7) | 94 (26.8) | 183 (30.3) | 0.017 | | Quartile 2 | 299 (27.6) | 83 (23.6) | 128 (21.2) | | Quartile 3 | 247 (22.8) | 98 (27.9) | 141 (23.3) | | Quartile 4 | 269 (24.8) | 76 (21.7) | 152 (25.2) | | Insurance (%) | Insured | 1025 (94.6) | 335 (95.4) | 587 (97.2) | 0.126 | | Uninsured | 49 (4.5) | 13 (3.7) | 12 (2.0) | | Unknown | 10 (0.9) | 3 (0.9) | 5 (0.8) | | Grade (%) | I | 1 (0.1) | 1 (0.3) | 0 (0.0) | 0.663 | | II | 26 (2.4) | 7 (2.0) | 20 (3.3) | | III | 1033 (95.3) | 334 (95.2) | 568 (94.0) | | IV | 24 (2.2) | 9 (2.6) | 16 (2.6) | | TNM stage (%) | I | 287 (26.5) | 44 (12.5) | 82 (13.6) | <0.001 | | II | 211 (19.5) | 45 (12.8) | 118 (19.5) | | III | 328 (30.3) | 128 (36.5) | 235 (38.9) | | IV | 258 (23.8) | 134 (38.2) | 169 (28.0) | | T stage (%) | T0/1 | 297 (27.4) | 60 (17.1) | 143 (23.7) | <0.001 | | T2 | 134 (12.4) | 28 (8.0) | 66 (10.9) | | T3 | 290 (26.8) | 88 (25.1) | 273 (45.2) | | T4 | 363 (33.5) | 175 (49.9) | 122 (20.2) | | N stage (%) | N0 | 492 (45.4) | 141 (40.2) | 242 (40.1) | <0.001 | | N1 | 237 (21.9) | 59 (16.8) | 223 (36.9) | | N2 | 129 (11.9) | 44 (12.5) | 76 (12.6) | | N3 | 226 (20.8) | 107 (30.5) | 63 (10.4) | | M stage (%) | M0 | 826 (76.2) | 217 (61.8) | 435 (72.0) | <0.001 | | M1 | 258 (23.8) | 134 (38.2) | 169 (28.0) | | Tumor size (%) | ≤2 cm | 187 (17.3) | 29 (8.3) | 72 (11.9) | <0.001 | | ≤5 cm | 320 (29.5) | 53 (15.1) | 185 (30.6) | | >5 cm | 257 (23.7) | 116 (33.0) | 135 (22.4) | | Unknown | 320 (29.5) | 153 (43.6) | 212 (35.1) | | Regional nodes examined (%) | ≤16 | 706 (65.1) | 236 (67.2) | 471 (78.0) | <0.001 | | >16 | 378 (34.9) | 115 (32.8) | 133 (22.0) | | Bone metastasis (%) | Yes | 24 (2.2) | 21 (6.0) | 28 (4.6) | 0.001 | | No | 1060 (97.8) | 330 (94.0) | 576 (95.4) | | Brain metastasis (%) | Yes | 3 (0.3) | 0 (0.0) | 3 (0.5) | 0.389 | | No | 1081 (99.7) | 351 (100.0) | 601 (99.5) | | Liver metastasis (%) | Yes | 32 (3.0) | 16 (4.6) | 36 (6.0) | 0.011 | | No | 1052 (97.0) | 335 (95.4) | 568 (94.0) | | Lung metastasis (%) | Yes | 24 (2.2) | 10 (2.8) | 27 (4.5) | 0.033 | | No | 1060 (97.8) | 341 (97.2) | 577 (95.5) | | Surgery (%) | No surgery | 357 (32.9) | 152 (43.3) | 318 (52.6) | <0.001 | | Surgery | 727 (67.1) | 199 (56.7) | 286 (47.4) | | Radiation (%) | No/unknown | 830 (76.6) | 282 (80.3) | 306 (50.7) | <0.001 | | Yes | 254 (23.4) | 69 (19.7) | 298 (49.3) | | Chemotherapy (%) | No/unknown | 440 (40.6) | 109 (31.1) | 128 (21.2) | <0.001 | | Yes | 644 (59.4) | 242 (68.9) | 476 (78.8) |
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