The Therapeutic Effectiveness Using Fluorescence-Guided Surgery for MRONJ

Table 2

The therapeutic effect of studies reporting on fluorescence-guided surgery for MRONJ.

Authors	Research types of	Surgical procedure	Number of cases	Number of lesions	MRONJ lesion staging				Mucosal healing rate	Inflammation remission rate
					0	I	II	III
Pautke et al., [14]	N-RCT	Tetracycline fluorescence	15	20	0	0	15	5	85.0%	NA
Assaf et al., [13]	N-RCT	Tetracycline fluorescence	20	23	0	2	10	11	91.3%	NA
Otto et al., [12]	N-RCT	Tetracycline fluorescence	54	65	1	14	42	8	86.2%	86.2%
Ristow et al., [16]	RCTs	Tetracycline fluorescence	20	26	0	3	20	3	88.5%	92.3%
		Autofluorescence	20	25	0	1	21	3	92.0%	94.0%
Giudice et al., [15]	RCTs	Autofluorescence	18	19	0	6	6	7	84.2%	95.0%
		Traditional technique	18	20	0	6	6	8	85.0%	89.5%
Otto et al., [11]	N-RCT	Autofluorescence	75	82	3	3	62	14	81.7%	NA