Using of Single-Layer Porcine Small Intestinal Submucosa in Urethroplasty on a Beagle Model

Figure 6

Surgical site urethra histological observation 12 w after operation. (a) Control, HE; (b) SIS, HE; (c) control, Mallory; (d) SIS, Mallory. The star marks the urethra in images (a), (b), and (d). A normal urethra was observed in images (a) and (b). SIS material was disintegrated and replaced by fibrous tissue. In image (c), a large number of hyperplastic and disordered collagen fibers can be seen, while in image (d), the original SIS material has been replaced by a regular arrangement of collagen.

(a)

(b)

(c)

(d)