Wenhua Juanbi Recipe Attenuates Rheumatoid Arthritis via Inhibiting miRNA-146a-Mediated Autophagy

Table 2

Characteristics of chemical components in WJR by UHPLC-Q-TOF/MS analysis.

No.	Component name	Retention time	Formula	Precursor mass	Found at mass	Mass error (ppm)	Detector count	Response
1	3-O-Angelioyl hydrellol	0.77	C20H22O6	358.141	359.151	1.4	1104	176
2	Ornithine	0.81	C5H12N2O2	132.089	133.097	1.4	6547	439
3	Alanine	0.82	C3H7NO2	89.047	90.0548	-1.6	719	636
4	Isoleucine	0.84	C6H13NO2	131.094	132.101	-0.3	5484	127
5	Betaine	0.92	C5H11NO2	117.078	118.086	-0.4	3696	3355
6	Coix lactone	1.44	C8H7NO3	165.042	166.0492	-4.3	778	632
7	2-Hydroxy-5-methylacetophenone	4.74	C9H10O2	150.068	151.0752	-1	3957	1890
8	Chlorogenic acid	5.45	C16H18O9	354.095	355.102	-0.2	16472	911
9	Danshensu methyl ester	5.46	C10H12O5	212.068	213.077	-0.2	13637	592
10	Elemisin	5.63	C12H16O3	208.109	209.117	-0.5	468	170
11	Luteolin	6.07	C15H10O6	286.047	287.055	3	760	616
12	5-Hydroxymethylfurfural	6.17	C6H6O3	126.031	127.039	0.5	5883	5470
13	Erythraline	6.19	C18H19NO3	297.136	298.144	1	9428	775
14	Ericin	6.19	C17H24O9	372.142	373.1489	-1.1	71733	379
15	Mesonine	6.32	C16H23NO5	309.157	310.164	-0.8	3788	3169
16	Phenylpropionic acid	6.88	C9H11NO2	165.078	166.086	-0.4	1396	274
17	Neobic Angelica ether	6.94	C17H16O6	316.094	317.102	0.3	33704	8608
18	Aglycone	7.18	C14H14O4	246.089	247.096	0.4	1083	107
19	Oxidized prehulin	7.21	C16H14O5	286.084	287.091	-0.3	688	520
20	Schiolaricin	7.32	C20H26O6	362.173	363.182	5.6	3669	1726
21	Pulsatilla	7.47	C10H8O4	192.042	193.049	0.4	788	703
22	Bikukuling	8.01	C20H17NO6	367.105	368.1131	0.8	410	125
23	3,4-Dihydroxycinnamic acid	8.04	C9H8O4	180.042	181.0498	1.5	677	547
24	Cimicifolin	8.06	C16H18O6	306.11	307.118	0.3	147038	118940
25	Coptisine	9.51	C19H13NO4	319.084	320.091	-0.2	2593	2062
26	d-Nandina	9.94	C20H21NO4	339.147	340.1541	-0.7	1352	493
27	Dehydroepapaverine	9.96	C21H23NO4	353.162	354.1696	-1.2	10972	8434
28	5-O-Methyl visamiol	10.24	C16H18O5	290.115	291.122	-1	25822	20625
29	Dihydrosanguinarine	10.24	C20H15NO4	333.100	334.1076	0.6	552	394
30	Tetrandine	10.58	C21H21NO4	351.147	352.154	-0.9	45978	10937
31	Spearmintine	10.62	C20H25NO3	327.183	328.1907	-0.2	560	322
32	Thymoloside	10.71	C21H26O10	438.152	439.1596	-0.6	24346	15557
33	Zanthoxylin	10.91	C11H6O4	202.026	203.033	-0.6	1016	804
34	Dehydrofumarine A	11.12	C22H23NO4	365.162	366.169	-1.3	57576	44710
35	Berberine	11.12	C20H17NO4	335.115	336.121	-3.4	2811	599
36	Honeysuckle	12.67	C20H24O7	376.152	377.159	-0.6	573	467
37	3’-O-Acetylchomellol	17.12	C17H18O6	318.11	319.116	-2.2	446	274
38	α-Monolinolenic esters	27.12	C21H38O4	354.277	355.2842	-0.2	1749	1429
39	Beta-cineol	30.49	C15H26O	222.198	223.205	-0.9	8938	359
40	Ergosterol	30.63	C28H44O	396.339	397.3435	-7.6	218	154
1	Arginine_1	0.76	C6H14N4O2	174.11168	173.1032	-6.8	2348	2163
2	Triolein	0.77	C57H104O6	884.78329	883.7745	-1.7	88	70
3	Mannitol	0.81	C6H14O6	182.07904	181.0706	-6.3	2390	1984
4	Glutamate_1	0.82	C5H9NO4	147.05316	146.044	-9.1	497	290
5	Ericin	0.82	C17H24O9	372.14203	371.1311	-9.8	1973	121
6	(2S,3S,4S,5R)-2,3,4,5,6-Pentahydroxyhexanoic acid	0.82	C6H12O7	196.0583	195.0501	-4.5	3188	3188
7	6-Sinapoylspinosin	0.83	C39H44O18	800.25276	799.2473	2.3	100086	99
8	Sinigrin_1	1.05	C10H17NO9S2	359.034	358.026	-1.3	24244	18775
9	Chlorogenic acid	5.21	C16H18O9	354.09508	353.085	-5.4	536	276
10	Sinapine	6.14	C16H23NO5	309.15762	354.1549	-2.7	4460	446
11	Cimicifugacin	7.04	C22H28O11	468.16316	467.1538	0.3	5583	3944
12	Berberine hydrogenated	9.39	C20H21NO4	339.14706	338.1389	-2.5	68	68
13	Dehydroepapaverine	10.08	C21H23NO4	353.162	352.153	-6	242	183
14	5-O-Methyl visamiol	13.87	C16H18O5	290.11542	289.1074	-2.6	101	96
15	Loganine	26.04	C17H26O10	390.1526	389.1487	8.7	721	537
16	Papaveric acid_2	26.15	C18H32O2	280.24023	279.2321	-2.9	402	338
17	Methyl pentadecanoate	27.4	C16H32O2	256.24023	255.232	-2.4	10845	9167
18	Thymoloside	27.4	C21H26O10	438.1526	437.143	-3.6	4142	1135
19	Octadecanoic acid_2	29.83	C18H36O2	284.27153	283.263	-1.2	12532	10275
20	Arachic acid	31.86	C20H40O2	312.30283	311.295	-0.3	1315	1044
21	Taroic acid_1	33.42	C22H44O2	340.33413	339.3257	-3.3	4302	3443
22	Octadecanoic acid_2	33.45	C18H36O2	284.27153	283.2629	-4.7	2431	1651
23	Beta-carotene_2	33.8	C35H60O6	576.43899	575.43	-2.2	25104	794
24	Myristic acid (tetradecanoic acid)_1	34.13	C14H28O2	228.20893	227.2	-0.9	1811	1307
25	Methyl hexadecanoate	34.13	C17H34O2	270.25588	269.249	2.9	961	457
26	Palmitoleic acid	34.13	C16H30O2	254.22458	253.2164	-3.6	1102	933
27	Methyl myristate	34.14	C15H30O2	242.22458	241.2167	-2.6	1204	627
28	Di-(2-ethyl)hexyl sebacate	34.15	C26H50O4	426.37091	425.362	-3.5	3618	373
29	Dehydrofumarine A	34.21	C22H23NO4	365.162	410.163	6.2	260	258
30	Marmarin A	34.21	C22H27NO4	369.19401	368.1875	0.8	142	142
31	Saulatine	34.21	C22H23NO6	397.15254	396.1451	-0.3	253	181