Antioxidant Mechanism of Renal and Hepatic Failure Prevention Related to Paracetamol Overdose by the Aqueous Extract of Amblygonocarpus andongensis Stem Bark

Figure 6

Microphotographs of rat kidneys (×200, hematoxylin-eosin stain). (a) Normal control. (b) Negative control. (c) Positive control treated with 0.9% normal saline. (d) Positive control treated with N-acetylcysteine. (e–g) Groups treated with aqueous extract of A. andongensis stem bark at doses of 125, 250, and 500 mg/kg, respectively. (h) Satellite control. (i) Satellite treated with aqueous extract of A. andongensis stem bark at the dose of 500 mg/kg. Gl: glomerulus; Us: urinary space; Dct: distal convoluted tubule; Pct: proximal convoluted tubule; LI: leukocyte infiltration; Gc: glomerular constriction; Dus: dilatation of the urinary space.

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