Antioxidant Mechanism of Renal and Hepatic Failure Prevention Related to Paracetamol Overdose by the Aqueous Extract of Amblygonocarpus andongensis Stem Bark

Table 2

Effect of AEAASB on some hematological parameters.

	Total leukocytes (×10^9/l)	Lymphocytes (%)	Granulocytes (%)	Red blood cells (×10^12/l)	Hematocrit (%)	Hemoglobin (g/dl)	Blood platelets (×10^9/l)
Normal control
Negative control	^♦♦		^♦♦♦	^♦♦♦	^♦♦♦	^♦
Positive control-PS
Positive control-NAC
AEAASB 125
AEAASB 250
AEAASB 500
Satellite control
Satellite AEAASB 500	●

Values are expressed as ; positive control-PS: treated with 0.9% normal saline; positive control-NAC: treated with N-acetylcysteine; AEAASB 125, AEAASB 250, AEAASB 500: groups treated with aqueous extract of A. andongensis stem bark at doses of 125, 250, and 500 mg/kg, respectively; satellite AEAASB 500: treated with aqueous extract of A. andongensis stem bark at the dose of 500 mg/kg. ^♦, ^♦♦, ^♦♦♦ significant difference compared to normal control, , , significant difference compared to negative control, ^● significant difference compared to satellite control.