Research Article

The Clinical Features and Treatment Strategy of Parathyroid Cancer: A Retrospective Analysis

Table 1

Characteristics of Patients with Parathyroid Carcinoma.

PatientAge[yr.]/sexClinical manifestationInitial calcium[mg/dl]PTH[pg/ml]Alkaline Phosphatase[IU/L]Ultrasound/CTThe extent of disease at the initial operationInvasion saw in operationFollow-up[month]Recurrence/metastases

146/FParathyroid nodule for 1 month8.611373.8Left parathyroid nodules; inhomogeneity; clear margins;cmTumor resection with limited resection of the neighboring thyroid glandN90N
250/FThyroid nodule for 2 months13.4804.6823.3Solid nodules in the right lobe of the thyroid; clear margins; regular morphology; cmTumor resection with limited resection of the neighboring thyroid gland; the ipsilateral central node dissectionN36N
339/FUrinary stones and hydronephrosis; multiple bone fractures; parathyroid occupation for 10 days15.831922733.8A solid nodule in the lower left parathyroid; clear margins; Regular morphology; cmTumor resection with limited resection of the neighboring thyroid glandN30N
470/MHematoma of the neck for 5 days with thyroid occupation10.32273.154The solid nodule in the middle of the right thyroid; clear margins; regular morphology; cmTumor resection with the right lobe and the isthmus of the ipsilateral thyroid gland; ipsilateral central node dissectionAdhesion with neighboring thyroid gland; neighboring muscles; carotid sheath20N
564/MWeakness in both lower extremities for 1 year;
Abdominal distension for 1 month;
Parathyroid occupation for 10 days
14.44189613Solid occupation of the right parathyroid; unclear margins; irregular morphology; cmEndoscopic right parathyroid resectionN48Local recurrence in 8 months after surgery
1 year after surgery, chest wall recurrence
2 years after surgery, distant metastases
656/MParathyroid occupation for 10 days10.8134.597.3A solid nodule of the right parathyroid; inhomogeneity; Clear margins; regular morphology; cmTumor resection with limited resection of the neighboring thyroid glandN12N
764/MThyroid occupation for 2 years;11.8425176.8A solid occupation in the left lobe of the thyroid; clear margins; regular morphology; cmTumor resection with ipsilateral hemithyroidectomyNeighboring thyroid gland; esophagus; recurrent laryngeal nerve10N