[Retracted] LRSAM1 E3 Ubiquitin Ligase Promotes Choriocarcinoma Progression and Metastasis via p53/p21 Signaling Impediment

Figure 3

LRSAM1 knockdown accelerates apoptotic process and inhibits EMT in choriocarcinoma cellular structures. (a) FACS analysis shows enhanced cell apoptotic process. (b) Western blot reveals upregulation of proapoptotic Bax, cleaved-caspase 3, cleaved-caspase 9, and impediment of anti-apoptotic Bcl-2 in transfected cellular structures. (c) In transfected cellular structures, Western blot reveals a greater expression of E-cadherin and a decreased expression of N-cadherin.

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