Research Article

Connections between Various Disorders: Combination Pattern Mining Using Apriori Algorithm Based on Diagnosis Information from Electronic Medical Records

Table 3

Association rules within the same ICD-10 “chapter”.

No.Association rules (ICD-10 codes)AntecedentConsequentSupportConfidenceLift

1Q44 -> Q61Congenital malformations of the gallbladder, bile ducts, and liverCystic kidney disease19.89%97.27%4.71
2K80, K20 -> K29Cholelithiasis and oesophagitisGastritis and duodenitis0.33%96.77%1.81
3Q61 -> Q44Cystic kidney diseaseCongenital malformations of the gallbladder, bile ducts, and liver19.89%96.40%4.71
4I66 -> I63Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarctionCerebral infarction5.94%96.05%1.46
5I66, I25 -> I63Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction chronic ischaemic heart diseaseCerebral infarction1.73%94.69%1.44
6I65 -> I63Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarctionCerebral infarction5.01%92.64%1.41
7K20 -> K29OesophagitisGastritis and duodenitis4.15%92.25%1.73
8R13 -> R47DysphagiaSpeech disturbances, not elsewhere classified12.15%90.91%5.77
9I70, I61 -> I10Atherosclerosis intracerebral haemorrhageEssential (primary) hypertension0.13%89.04%1.24
10G80 -> G40Cerebral palsyEpilepsy1.35%86.54%3.94
11I61, I69 -> I10Intracerebral haemorrhage sequelae of cerebrovascular diseaseEssential (primary) hypertension1.11%86.32%1.20
12I61, I25 -> I10Intracerebral haemorrhagechronic ischaemic heart diseaseEssential (primary) hypertension0.64%86.14%1.20
13K21 -> K29Gastroesophageal reflux diseaseGastritis and duodenitis4.15%85.71%1.61
14I20, I69 -> I10Angina pectoris sequelae of cerebrovascular diseaseEssential (primary) hypertension0.39%84.78%1.18
15I70, I69 -> I10Atherosclerosis sequelae of cerebrovascular diseaseEssential (primary) hypertension0.20%84.48%1.18
16I25, I69 -> I10Chronic ischaemic heart disease sequelae of cerebrovascular diseaseEssential (primary) hypertension1.10%84.19%1.17
17I25, I71 ->I10Chronic ischaemic heart disease aortic aneurysm and dissectionEssential (primary) hypertension0.17%83.84%1.17
18I20, I66 -> I10Angina pectoris occlusion and stenosis of cerebral arteries, not resulting in cerebral infarctionEssential (primary) hypertension0.54%83.44%1.16
19I80, I61 -> I10Phlebitis and thrombophlebitis intracerebral haemorrhageEssential (primary) hypertension0.12%83.33%1.16
20I20, I61 -> I10Angina pectoris intracerebral haemorrhageEssential (primary) hypertension0.22%82.71%1.15
21I61, I63 -> I10Intracerebral haemorrhage cerebral infarctionEssential (primary) hypertension2.20%82.41%1.15
22J03, J04 -> J18Acute tonsillitis acute laryngitis and tracheitisPneumonia, organism unspecified0.48%82.22%1.47
23I61 -> I10Intracerebral haemorrhageEssential (primary) hypertension3.99%82.09%1.15
24I66, I61 -> I10Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction intracerebral haemorrhageEssential (primary) hypertension0.21%82.03%1.14
25I50, I65 -> I10Heart failure occlusion and stenosis of precerebral arteries, not resulting in cerebral infarctionEssential (primary) hypertension0.21%81.54%1.14
26I71, I63 -> I10Aortic aneurysm and dissection cerebral infarctionEssential (primary) hypertension0.24%81.25%1.13
27I70, I10 -> I63Atherosclerosis
essential (primary) hypertension
Cerebral infarction3.40%81.08%1.23
28I70 -> I63AtherosclerosisCerebral infarction5.18%81.05%1.23
29I66, I25 -> I10Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction chronic ischaemic heart diseaseEssential (primary) hypertension1.48%80.97%1.13
30J21 -> J18Acute bronchiolitisPneumonia, organism unspecified2.08%80.80%1.44
31K65, K70 ->K74Peritonitis
alcoholic liver disease
Fibrosis and cirrhosis of the liver0.55%80.65%5.85
32I20, I65 ->I10Angina pectoris occlusion and stenosis of precerebral arteries, not resulting in cerebral infarctionEssential (primary) hypertension0.67%80.43%1.12
33I66, I69 -> I10Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction sequelae of cerebrovascular diseaseEssential (primary) hypertension0.47%80.34%1.12
34I71 -> I10Aortic aneurysm and dissectionEssential (primary) hypertension0.49%80.00%1.12
35I70, I25 -> I63Atherosclerosis
chronic ischaemic heart disease
Cerebral infarction1.77%79.53%1.21
36I69 -> I10Sequelae of cerebrovascular diseaseEssential (primary) hypertension4.05%79.39%1.11
37K26 -> K29Duodenal ulcerGastritis and duodenitis3.91%79.06%1.48
38I65, I69 -> I10Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction sequelae of cerebrovascular diseaseEssential (primary) hypertension0.28%78.77%1.10
39I63, I69 -> I10Cerebral infarction sequelae of cerebrovascular diseaseEssential (primary) hypertension3.04%78.47%1.09
40I25, I65 -> I10Chronic ischaemic heart disease occlusion and stenosis of precerebral arteries, not resulting in cerebral infarctionEssential (primary) hypertension1.52%78.17%1.09
41I66, I65 -> I10Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction occlusion and stenosis of precerebral arteries, not resulting in cerebral infarctionEssential (primary) hypertension1.29%77.95%1.09
42J21, J03 -> J18Acute bronchiolitis acute tonsillitisPneumonia, organism unspecified0.40%77.50%1.38
43H40, H04 ->H25Glaucoma
disorders of lacrimal system
Senile cataract0.72%77.42%2.04
44I95 -> I63HypotensionCerebral infarction0.13%77.38%1.17
45C65 -> C64Malignant neoplasm of the renal pelvisMalignant neoplasm of the kidney, except the renal pelvis0.47%77.19%27.80
46R47 -> R13Speech disturbances, not elsewhere classifiedDysphagia12.15%77.18%5.77
47J04 -> J18Acute laryngitis and tracheitisPneumonia, organism unspecified2.14%76.38%1.36
48I70, I50 -> I10Atherosclerosis heart failureEssential (primary) hypertension0.34%76.15%1.06
49I70, I20 -> I63Atherosclerosis
angina pectoris
Cerebral infarction0.71%76.14%1.16
50I05 -> I48Rheumatic mitral valve diseasesArtrial fibrillation and flutter0.43%75.89%8.25
51I70, I20 -> I10Atherosclerosis angina pectorisEssential (primary) hypertension0.70%75.49%1.05
52I70, I66 -> I10Atherosclerosis occlusion and stenosis of precerebral arteries, not resulting in cerebral infarctionEssential (primary) hypertension0.45%75.17%1.05
53I20, I63 ->I10Angina pectoris cerebral infarctionEssential (primary) hypertension7.95%75.10%1.05
54B91 -> B18Sequelae of poliomyelitisChronic viral hepatitis0.31%75.00%2.19
55H72 -> H66Perforation of tympanic membraneSuppurative and unspecified otitis media0.72%75.00%16.17
56I48, I66 -> I10Artrial fibrillation and flutter occlusion and stenosis of precerebral arteries, not resulting in cerebral infarctionEssential (primary) hypertension0.27%75.00%1.05
57I50, I69 -> I10Heart failure sequelae of cerebrovascular diseaseEssential (primary) hypertension0.35%74.89%1.04
58J03, J20 -> J18Acute tonsillitis and acute bronchitisPneumonia, organism unspecified1.93%74.44%1.33
59I66, I50 -> I10Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction heart failureEssential (primary) hypertension0.19%74.42%1.04
60I66, I63 -> I10Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarctionEssential (primary) hypertension4.42%74.34%1.04
61I21 -> I25Acute myocardial infarctionChronic ischaemic heart disease4.70%74.21%1.79
62I66 -> I10Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarctionEssential (primary) hypertension4.58%74.08%1.03
63I80, I69 ->I10Phlebitis and thrombophlebitis sequelae of cerebrovascular diseaseEssential (primary) hypertension0.12%74.07%1.03
64I48, I70 -> I63Artrial fibrillation and flutter atherosclerosisCerebral infarction0.32%74.07%1.12
65J03 -> J18Acute tonsillitisPneumonia, organism unspecified9.44%74.06%1.32
66G97 -> G91Postprocedural disorders of nervous system, not elsewhere classifiedHydrocephalus1.71%74.03%8.32
67I70, I25 ->I10Atherosclerosis chronic ischaemic heart diseaseEssential (primary) hypertension1.65%74.00%1.03
68I63 -> I10Cerebral infarctionEssential (primary) hypertension48.68%73.86%1.03
69D06 -> D25Carcinoma in situ of the cervix uteriLeiomyoma of the uterus3.04%73.38%3.53
70I00 -> I10Rheumatic fever without mention of heart involvementEssential (primary) hypertension0.12%73.17%1.02
71I65, I63 -> I10Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarctionEssential (primary) hypertension3.66%72.95%1.02
72I25, I63 -> I10Chronic ischaemic heart disease and cerebral infarctionEssential (primary) hypertension16.95%72.90%1.02
73I65 -> I10Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarctionEssential (primary) hypertension3.94%72.78%1.02
74I48, I70 -> I10Artrial fibrillation and flutter atherosclerosisEssential (primary) hypertension0.32%72.22%1.01
75K44 -> K29Diaphragmatic herniaGastritis and duodenitis1.68%72.21%1.35
76J04, J20 ->J18Acute laryngitis and tracheitis acute bronchitisPneumonia, organism unspecified0.53%72.17%1.29
77H04 ->H25Disorders of lacrimal systemSenile cataract5.09%71.91%1.89
78S93 -> S82Dislocation, sprain, and strain of joints and ligaments at ankle and foot levelFracture of the lower leg, including the ankle1.61%71.70%4.85
79S32, S06 -> S22Fracture of the lumbar spine and pelvis
intracranial injury
Fracture of the rib(s), sternum, and thoracic spine2.76%70.65%2.08
80E02, E79 -> E11Subclinical iodine-deficiency hypothyroidism disorders of purine and pyrimidine metabolismType 2 diabetes mellitus0.20%70.27%1.04
81F84 -> F79Pervasive developmental disordersUnspecified mental retardation18.96%70.18%2.64
82C19 -> C18Malignant neoplasm of the rectosigmoid junctionMalignant neoplasm of the colon0.15%70.00%9.69
83C19 -> C20Malignant neoplasm of the rectosigmoid junctionMalignant neoplasm of the rectum0.15%70.00%9.78
84I10, I74 -> I63Essential (primary) hypertension arterial embolism and thrombosisCerebral infarction0.24%70.00%1.06
85E77, E02 -> E11Disorders of glycoprotein metabolism
subclinical iodine-deficiency hypothyroidism
Type 2 diabetes mellitus0.17%69.70%1.03
86F80 -> F84Specified developmental disorders of speech and languagePervasive developmental disorders24.88%69.08%2.56
87K65, K80 -> K74Peritonitis and cholelithiasisFibrosis and cirrhosis of the liver0.49%68.75%4.99
88I80, I25 -> I63Phlebitis and thrombophlebitis
chronic ischaemic heart disease
Cerebral infarction0.27%68.00%1.03
89I10 -> I63Essential (primary) hypertensionCerebral infarction48.68%67.92%1.03
90K70 -> K74Alcoholic liver diseaseFibrosis and cirrhosis of the liver2.57%67.64%4.91
91S32, S02 -> S22Fracture of the lumbar spine and pelvis and fracture of the skull and facial bonesFracture of the rib(s), sternum, and thoracic spine2.12%66.67%1.96
92J03, J40 -> J18Acute tonsillitis and bronchitis, not specified as acute or chronicPneumonia, organism unspecified0.77%65.57%1.17
93K25 -> K29Gastric ulcerGastritis and duodenitis2.88%64.68%1.21
94K58 -> K29Irritable bowel syndromeGastritis and duodenitis0.71%64.65%1.21
95K65 -> K74PeritonitisFibrosis and cirrhosis of the liver2.98%62.41%4.53
96K57 -> K29Diverticular disease of the intestineGastritis and duodenitis1.25%62.15%1.16
97J20 -> J18Acute bronchitisPneumonia, organism unspecified6.98%62.11%1.11