The Relationship between VEGFC Gene Polymorphisms and Autoimmune Thyroiditis

Table 2

Associations of rs7664413, rs11947611, rs2046463, and rs3775194 in VEGFC gene with AITD, GD, and HT.

		AITD; (%)	NC; (%)	P value; AITD vs NC	GD; (%)	P value; GD vs NC	HT; (%)	P value; HT vs NC
rs7664413	CC	495 (45.7)	350 (44.1)	0.652	293 (43.9)	0.364	202 (48.4)	0.238
	TT	122 (11.3)	85 (10.7)		87 (13.0)		35 (8.4)
	TC	467 (43.1)	359 (45.2)		288 (43.1)		180 (43.2)
	C	1457 (67.2)	1059 (66.7)	0.739	874 (65.4)	0.470	584 (70.0)	0.095
	T	711 (32.8)	529 (33.3)		462 (34.6)		250 (30.0)
rs11947611	AA	410 (37.8)	318 (40.1)	0.527	251 (37.6)	0.534	159 (38.1)	0.765
	GG	167 (15.4)	111 (14.0)		104 (15.6)		63 (15.1)
	AG	507 (46.8)	365 (46.0)		313 (46.9)		195 (46.8)
	A	1327 (61.2)	1001 (63.0)	0.255	815 (61.0)	0.259	513 (61.5)	0.461
	G	841 (38.8)	587 (37.0)	0.600	521 (39.0)		321 (38.5)
rs2046463	AA	492 (45.4)	347 (43.7)		291 (43.6)	0.315	201 (48.2)	0.224
	GG	123 (11.3)	85 (10.7)		88 (13.2)		35 (8.4)
	AG	469 (43.3)	362 (45.6)		289 (43.3)		181 (43.4)
	A	1453 (67.0)	1056 (66.5)	0.737	871 (65.2)	0.459	583 (69.9)	0.089
	G	715 (33.0)	532 (33.5)		465 (34.8)		251 (30.1)
rs3775194	CC	12 (1.1)	4 (0.5)	0.029	8 (1.2)	0.092	4 (1.0)	0.052
	GG	906 (83.6)	636 (80.1)		553 (82.8)		354 (84.9)
	CG	166 (15.3)	154 (19.4)		107 (16.0)		59 (14.1)
	C	190 (8.8)	162 (10.2)	0.135	123 (9.1)	0.310	67 (8.0)	0.083
	G	1978 (91.2)	1426 (89.8)		1213 (90.9)		767 (92.0)