The Relationship between VEGFC Gene Polymorphisms and Autoimmune Thyroiditis

Table 3

Associations of four polymorphisms models in VEGFC with AITD before and after adjusting for confounders.

Comparison models	Unadjusted estimates		Adjusted estimates
	OR (95% CI)	value	OR(95% CI)	value
rs7664413
Allele model	0.98 (0.85-1.12)	0.74	0.97 (0.84-1.12)	0.69
Dominant model	0.94 (0.78-1.13)	0.50	0.93 (0.77-1.12)	0.45
Recessive model	1.06 (0.79-1.42)	0.71	1.06 (0.78-1.43)	0.72
Overdominant model	0.92 (0.76-1.10)	0.36	0.91 (0.75-1.10)	0.32
rs11947611
Allele model	1.08 (0.95-1.23)	0.26	1.06 (0.92-1.21)	0.43
Dominant model	1.10 (0.91-1.32)	0.33	1.07 (0.89-1.30)	0.47
Recessive model	1.12 (0.86-1.45)	0.39	1.08 (0.83-1.40)	0.59
Overdominant model	1.03 (0.86-1.24)	0.73	1.03 (0.86-1.24)	0.74
rs2046463
Allele model	0.98 (0.85-1.12)	0.74	0.97 (0.84-1.12)	0.69
Dominant model	0.93 (0.78-1.12)	0.47	0.93 (0.77-1.12)	0.43
Recessive model	1.07 (0.80-1.43)	0.66	1.06 (0.79-1.43)	0.69
Overdominant model	0.91 (0.76-1.09)	0.32	0.90 (0.75-1.09)	0.29
rs3775194
Allele model	0.85 (0.68-1.05)	0.14	0.83 (0.66-1.05)	0.12
Dominant model	0.79 (0.62-1.00)	0.05	0.79 (0.62-1.00)	0.05
Recessive model	2.21 (0.71-6.88)	0.15	1.91 (0.60-6.08)	0.25
Overdominant model	0.75 (0.59-0.96)	0.02	0.75 (0.59-0.96)	0.02