The Relationship between VEGFC Gene Polymorphisms and Autoimmune Thyroiditis

Table 4

Associations of four polymorphisms models in VEGFC with male AITD before and after adjusting for confounders.

Comparison models	Unadjusted estimates		Adjusted estimates
	OR (95% CI)	value	OR (95% CI)	value
rs7664413
Allele model	1.07 (0.83-1.37)	0.60	1.05 (0.82-1.34)	0.72
Dominant model	1.01 (0.72-1.40)	0.96	0.98 (0.70-1.37)	0.90
Recessive model	1.32 (0.78-2.23)	0.30	1.30 (0.77-2.21)	0.33
Overdominant model	0.90 (0.65-1.26)	0.54	0.88 (0.63-1.23)	0.46
rs11947611
Allele model	1.26 (0.98-1.61)	0.07	1.25 (0.97-1.60)	0.08
Dominant model	1.20 (0.86-1.69)	0.28	1.16 (0.82-1.63)	0.40
Recessive model	1.71 (1.04-2.82)	0.04	1.79 (1.08-2.98)	0.02
Overdominant model	0.95 (0.68-1.32)	0.74	0.89 (0.64-1.24)	0.49
rs2046463
Allele model	1.05 (0.82-1.35)	0.68	1.03 (0.81-1.33)	0.79
Dominant model	0.98 (0.71-1.37)	0.92	0.96 (0.68-1.34)	0.79
Recessive model	1.32 (0.78-2.23)	0.30	1.30 (0.77-2.21)	0.33
Overdominant model	0.88 (0.63-1.23)	0.45	0.86 (0.62-1.20)	0.38
rs3775194
Allele model	0.72 (0.48-1.09)	0.12	0.74 (0.49-1.12)	0.15
Dominant model	0.65 (0.42-1.00)	0.05	0.66 (0.43-1.02)	0.06
Recessive model	——	0.03	——	0.02
Overdominant model	0.59 (0.38-0.92)	0.02	0.60 (0.38-0.94)	0.02