Research Article
The Relationship between VEGFC Gene Polymorphisms and Autoimmune Thyroiditis
Table 5
Allele and genotype distributions of VEGF loci in subgroups of HT patients.
| | | Female controls
(%) | Female HT (%) | Unadjust/adjust value | Male controls (%) | Male HT (%) | Unadjust/adjust value |
| | rs7664413 | CC | 207 (43.4) | 170 (48.3) | 0.208 | | 143 (45.1) | 32 (49.2) | 0.831 | | | TT | 54 (11.3) | 29 (8.2) | | | 31 (9.8) | 6 (9.2) | | | | TC | 216 (45.2) | 153 (43.5) | | | 143 (45.1) | 27 (41.5) | | | | C | 493 (70.0) | 630 (66.0) | 0.082 | 0.07 | 429 (67.7) | 91 (70.0) | 0.600 | 0.49 | | T | 211 (30.0) | 324 (34.0) | | | 205 (32.3) | 39 (30.0) | | | | rs11947611 | AA | 185 (38.8) | 136 (38.6) | 0.627 | | 133 (42.0) | 23 (35.4) | 0.120 | | | GG | 80 (16.8) | 51 (14.5) | | | 31 (9.7) | 12 (18.5) | | | | AG | 212 (44.4) | 165 (46.9) | | | 153 (48.3) | 30 (46.1) | | | | A | 582 (61.0) | 437 (62.1) | 0.660 | 0.69 | 419 (66.1) | 76 (58.5) | 0.091 | 0.19 | | G | 372 (39.0) | 267 (37.9) | | | 215 (33.9) | 54 (41.5) | | | | rs2046463 | AA | 206 (43.2) | 169 (48.0) | 0.212 | | 141 (44.5) | 32 (49.2) | 0.780 | | | GG | 54 (11.3) | 29 (8.2) | | | 31 (9.8) | 6 (9.2) | | | | AG | 217 (45.5) | 154 (43.8) | | | 145 (45.7) | 27 (41.5) | | | | A | 629 (65.9) | 492 (69.9) | 0.085 | 0.07 | 427 (67.4) | 91 (70.0) | 0.550 | 0.46 | | G | 325 (34.1) | 212 (30.1) | | | 207 (32.6) | 39 (30.0) | | | | rs3775194 | CC | 4 (0.8) | 3 (0.9) | 0.506 | | 0 (0) | 1 (1.5) | 0.048 | | | GG | 388 (81.3) | 297 (84.4) | | | 248 (78.2) | 57 (87.7) | | | | CG | 85 (17.8) | 52 (14.8) | | | 69 (21.8) | 7 (10.8) | | | | C | 93 (9.7) | 58 (8.2) | 0.290 | 0.23 | 69 (10.9) | 9 (6.9) | 0.140 | 0.17 | | G | 861 (90.3) | 646 (91.8) | | | 565 (89.1) | 121 (93.1) | | |
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