Association of TP53 rs1042522 C>G Polymorphism with Glioma Risk in Chinese Children

Table 1

Association between TP53 rs1042522 C>G polymorphism and glioma risk.

Genotype	Cases ()	Controls ()	^a	Crude OR (95% CI)		Adjusted OR (95% CI)^b	^b
rs1042522 ()
CC	54 (31.58)	65 (28.51)		1.00		1.00
CG	80 (46.78)	117 (51.32)		0.82 (0.52-1.30)	0.406	0.83 (0.52-1.32)	0.433
GG	37 (21.64)	46 (20.18)		0.97 (0.55-1.70)	0.911	1.01 (0.57-1.78)	0.981
Additive			0.822	0.97 (0.73-1.28)	0.822	0.99 (0.74-1.31)	0.922
Dominant	117 (68.42)	163 (71.49)	0.507	0.86 (0.56-1.33)	0.507	0.88 (0.57-1.36)	0.564
Recessive	134 (78.36)	182 (79.82)	0.722	1.09 (0.67-1.78)	0.721	1.13 (0.69-1.85)	0.630

OR: odds ratio; CI: confidence interval; HWE: Hardy-Weinberg equilibrium. ^a test for genotype distributions between glioma patients and cancer-free controls. ^bAdjusted for age and gender.