Anti-Inflammatory Effects of Phlebia sp. Extract in Lipopolysaccharide-Stimulated RAW 264.7 Macrophages

Figure 5

Inhibitory effect of PSE on the activation of AP-1 signaling. The cells were pretreated 1 μg/mL LPS for 1 h and treated with 10 and 50 μg/mL PSE for 3 h. Expression of c-Jun, p-c-Jun, c-Fos, and p-c-Fos were determined by Western blot analysis (a). The ratios of c-Jun (b), p-c-Jun (c), c-Fos (d), and p-c-Fos (e) are shown. Data are presented as from three independent experiments. value < 0.05 was considered statistically significant by Duncan’s test.

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