SARS-CoV-2 Induces Expression of Cytokine and MUC5AC/5B in Human Nasal Epithelial Cell through ACE 2 Receptor

<div>The effects of spike protein RBD on ACE2 and TMPRSS2 expression in the cultured human nasal epithelial cell. Spike protein RBD significantly increased ACE2 mRNA expression in real-time PCR (a). Spike protein RBD significantly increased TMPRSS2 mRNA expression in real-time PCR (b). Three independent experiments were performed. 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Sp. RBD: spike protein receptor binding domain; ACE2: angiotensin converting enzyme 2; TMPRSS2: transmembrane protease serine subtype 2.</div>

BioMed Research International

fig1

Figure 1

Figure 1: SARS-CoV-2 Induces Expression of Cytokine and MUC5AC/5B in Human Nasal Epithelial Cell through ACE 2 Receptor 