Research Article

Intravoxel Incoherent Motion-Diffusion-Weighted MRI for Investigation of Delayed Graft Function Immediately after Kidney Transplantation

Table 4

The diagnostic efficacy of IVIM parameters in distinguishing early graft function from delayed graft function groups as well as in distinguishing delayed graft function without complication from delayed graft function with complication.

Cut-off value95% of CISensitivity (%)Specificity (%)PPV (%)NPV (%) value

EGF vs. DGF
ROI of entire renal parenchyma
(μm2/msec)1.860.8960.788-1.00076.991.383.391.3<0.001
(%)15.20.8930.781-1.00092.382.67582.6<0.001
(μm2/msec)1.930.9430.868-1.00084.691.384.691.3<0.001
ROI of graft renal cortex
(μm2/msec)1.740.8230.687-0.95810052.254.252.20.001
(%)15.20.8440.715-0.97492.373.966.773.90.001
(μm2/msec)1.950.8860.781-0.99176.98776.987<0.001
ROI of graft renal medulla
(μm2/msec)1.80.8930.760-1.00076.9100100100<0.001
(%)14.80.8850.771-0.99892.378.370.678.3<0.001
(μm2/msec)1.810.9430.840-1.00092.395.792.395.7<0.001
DGFwoC vs DGFwC
ROI of graft renal cortex
(%)12.30.8490.683-1.00076.99090.9900.006

EGF: early graft function; DGFwoC: delayed graft function without complication; DGFwC: delayed graft function with complication; : slow diffusion coefficient; : fast diffusion coefficient; : perfusion fraction; : apparent diffusion coefficient; : area under the curve; : positive predictive value; : negative predictive value; CI: confidence interval.