circZNF91 Promotes the Malignant Phenotype of Chronic Lymphocytic Leukemia Cells by Targeting the miR-1283/WEE1 Axis

Figure 4

Overexpression of miR-1283 inhibits the proliferation of CLL cells and induces apoptosis and G1/S arrest. Cells were transfected with miR-NC and miR-1283-mimic. (a) CCK-8 proliferation assay, (b) EdU incorporation assay, (c) apoptosis assay, (d) cell cycle analysis, and (e) Western blot analysis of Ki-67 cleaved caspase 3 and CCND1 (cyclin D) were performed in cells (miR-NC and miR-1283).

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