circZNF91 Promotes the Malignant Phenotype of Chronic Lymphocytic Leukemia Cells by Targeting the miR-1283/WEE1 Axis

Figure 6

The miR-1283/WEE1 axis mediates the effect of circZNF91. Cells were transfected with si-NC or si-circZNF91. In the si-circ-ZNF91 group, cells were further cotransfected with the miR-1283 inhibitor or WEE1 overexpression vector. (a) The expression levels of WEE1 protein in the above cells were detected by Western blot. (b) Cell proliferation, (c) EdU incorporation assay, (d) apoptosis assay, (e) cell cycle analysis, and (f) protein expression levels of Ki-67, cleaved caspase 3, and CCND1 were analyzed by Western blot.

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