Research Article

Network Pharmacology and Molecular Docking Validation to Reveal the Pharmacological Mechanisms of Kangai Injection against Colorectal Cancer

Table 2

Molecular docking.

Hub genesPDB enter IDPDB ligand IDGrid box dimension (center , , )Grid box size (, , ) (Å)CompoundBinding energy (kcal/mol)

TP535ab992O123.753, 104.322, -48.22340, 40, 40 ÅFormononetin-5.5
VEGFA5 t89NAG-97.543, 23.676, 28.70840, 40, 40 ÅGinsenoside F1-5.0
EGFR6hveGUW-6.005, 14.401, 12.14640, 40, 40 ÅCalycosin-0.8
EGFR6hveGUW-4.681, 5.36, 28.57340, 40, 40 ÅFormononetin-6.8
TNF6oozA6Y-12.439, -1.289, 18.73340, 40, 40 ÅCalycosin-7-glucoside-4.5
ESR11x7rGEN15.587, 32.224, 22.30440, 40, 40 ÅCalycosin-7.6
ESR11x7rGEN15.587, 32.224, 22.30440, 40, 40 ÅFormononetin-7.8
STAT36njsKQV13.498, 54.118, 0.140, 40, 40 ÅGinsenoside F1-5.5
HSP90AA12xjxXJX14.101, -2.869, 5.07240, 40, 40 ÅGinsenoside F1-6.6
AR3gjhGAP15.362, 4.093, 26.69140, 40, 40 ÅCalycosin-7.8
AR3gjhGAP15.362, 4.093, 26.69140, 40, 40 ÅFormononetin-7.5
AR2piqRB1-36.156, -9.368, 219.77940, 40, 40 ÅCalycosin-7-glucoside0
AR4oedDHT-27.579, 2.536, -4.73840, 40, 40 ÅGinsenoside Rg426.4
HDAC1-5w5kK70-16.926, 31.012, 3.32940, 40, 40 ÅOxymatrine-7.0
MMP92ovx4MR71.85, 12.27, 54.26240, 40, 40 ÅGinsenoside Rg4-7.2
MMP92ovz5MR70.536, 17.075, 53.27740, 40, 40 ÅOxymatrine-6.9