Intermittent Hydrostatic Pressure Promotes Cartilage Repair in an Inflammatory Environment through Hippo-YAP Signaling In Vitro and In Vivo

Figure 1

(a) The knee standing X-ray images of OA patients at different stages (the Kellgren-Lawrence score I-IV). (b) Immunohistochemistry staining images of YAP expression in the articular cartilage cells between the OA and control groups. (c) The significantly positive correlation of YAP⁺ chondrocytes in the OA group with the K-L score negatively (). (d) Immunohistochemistry staining images of p-YAP expression in the articular cartilage cells between the OA and control groups. (e) The significantly positive correlation of p-YAP⁺ chondrocytes in the OA group with the K-L score (). (f) Western blotting images of YAP1 and p-YAP1 expressions of the OA and control groups. (g) Western blotting images of YAP1 in the OA group and the negative correlation with the K-L scores ().

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