Research Article
Controlling Nutritional Status (CONUT) as a Novel Postoperative Prognostic Marker in Breast Cancer Patients: A Retrospective Study
| | Parameters | All patients () | | value | Control group () | | value | Treatment group (194) | | value | | Cases (n) | LOW 229 | HIGH 152 | Low 111 | High 76 | Low 118 | High 76 |
| | Age (years) | | | 1.372 | 0.241 | | | 1.503 | 0.220 | | | 0.251 | 0.617 | | < 50 | 108(57.14%) | 81(42.86%) | | | 44(54.32%) | 37(45.68%) | | | 64(59.26%) | 44(40.74%) | | | | ≥ 50 | 121(63.02%) | 71(36.98%) | | | 67(63.21%) | 39(36.79%) | | | 54(62.79%) | 32(37.21%) | | | | Marital status | | | 1.975 | 0.577 | | | | | | | 2.712 | 0.438 | | Married | 214(59.78%) | 144(40.22%) | | | 110(60.11%) | 73(39.89%) | | | 104(59.43%) | 71(40.57%) | | | | Unmarried | 10(76.92%) | 3(23.08%) | | | 1(50.00%) | 1(50.00%) | | | 9(81.82%) | 2(18.18%) | | | | Divorced | 2(50.00%) | 2(50.00%) | | | 0(0.00%) | 0(0.00%) | | | 2(50.00%) | 2(50.00%) | | | | Widowed | 3(50.00%) | 3(50.00%) | | | 0(0.00%) | 2(100.00%) | | | 3(75.00%) | 1(25.00%) | | | | Occupation | | | 1.560 | 0.456 | | | 2.195 | 0.334 | | | 1.821 | 0.401 | | Mental worker | 82(56.94%) | 62(43.06%) | | | 26(50.98%) | 25(49.02%) | | | 56(60.22%) | 37(39.78%) | | | | Manual worker | 53(58.89%) | 37(41.11%) | | | 37(62.71%) | 22(37.29%) | | | 16(51.61%) | 15(48.39%) | | | | Others | 94(63.95%) | 53(36.05%) | | | 48(62.34%) | 29(37.66%) | | | 46(65.71%) | 24(34.29%) | | | | Weight (kg) | | | 10.161 | 0.001 | | | 11.232 | 0.001 | | | 1.342 | 0.247 | | < 62 | 90(51.43%) | 85(48.57%) | | | 41(46.59%) | 47(53.41%) | | | 49(56.32%) | 38(43.68%) | | | | ≥ 62 | 139(67.48%) | 67(32.52%) | | | 70(70.71%) | 29(29.29%) | | | 69(64.49%) | 38(35.51%) | | | | Height (m) | | | 0.263 | 0.608 | | | 1.136 | 0.286 | | | 0.094 | 0.760 | | < 1.58 | 101(61.59%) | 63(38.41%) | | | 57(63.33%) | 33(36.67%) | | | 44(59.46%) | 30(40.54%) | | | | ≥ 1.58 | 128(58.99%) | 89(41.01%) | | | 54(55.67%) | 43(44.33%) | | | 74(61.67%) | 46(38.33%) | | | | BMI | | | 2.270 | 0.132 | | | 3.020 | 0.082 | | | 0.178 | 0.673 | | < 24.45 | 107(56.32%) | 83(43.68%) | | | 47(52.81%) | 42(47.19%) | | | 60(59.41%) | 41(40.59%) | | | | ≥ 24.45 | 122(63.87%) | 69(36.13%) | | | 64(65.31%) | 34(34.69%) | | | 58(62.37%) | 35(37.63%) | | | | Family history | | | 0.047 | 0.829 | | | 0.011 | 0.916 | | | 0.044 | 0.835 | | No | 171(60.42%) | 112(39.58%) | | | 84(59.57%) | 57(40.43%) | | | 87(61.27%) | 55(38.73%) | | | | Yes | 58(59.18%) | 40(40.82%) | | | 27(58.70%) | 19(41.30%) | | | 31(59.62%) | 21(40.38%) | | | | Menarche age (year) | | | 0.062 | 0.802 | | | 0.211 | 0.646 | | | 0.002 | 0.960 | | < 14 | 80(59.26%) | 55(40.74%) | | | 33(56.90%) | 25(43.10%) | | | 47(61.04%) | 30(38.96%) | | | | ≥ 14 | 149(60.57%) | 97(39.43%) | | | 78(60.47%) | 51(39.53%) | | | 71(60.68%) | 46(39.32%) | | | | Menopause | | | 1.419 | 0.233 | | | 0.883 | 0.347 | | | 0.588 | 0.443 | | No | 126(57.53%) | 93(42.47%) | | | 58(56.31%) | 45(43.69%) | | | 68(58.62%) | 48(41.38%) | | | | Yes | 103(63.58%) | 59(36.42%) | | | 53(63.10%) | 31(36.90%) | | | 50(64.10%) | 28(35.90%) | | | | ABO blood type | | | 0.962 | 0.811 | | | 3.076 | 0.381 | | | 1.815 | 0.612 | | A | 55(61.80%) | 34(38.20%) | | | 28(66.67%) | 14(33.33%) | | | 27(57.45%) | 20(42.55%) | | | | B | 71(61.74%) | 44(38.26%) | | | 36(64.29%) | 20(35.71%) | | | 35(59.32%) | 24(40.68%) | | | | O | 81(59.56%) | 55(40.44%) | | | 38(52.78%) | 34(47.22%) | | | 43(67.19%) | 21(32.81%) | | | | AB | 22(53.66%) | 19(46.34%) | | | 9(52.94%) | 8(47.06%) | | | 13(54.17%) | 11(45.83%) | | | | Tumor site | | | 0.636 | 0.801 | | | 0.086 | 0.769 | | | 0.004 | 0.949 | | Right | 113(60.75%) | 73(39.25%) | | | 55(60.44%) | 36(39.56%) | | | 58(61.05%) | 37(38.95%) | | | | Left | 116(59.49%) | 79(40.51%) | | | 56(58.33%) | 40(41.67%) | | | 60(60.61%) | 39(39.39%) | | | | Type of surgery | | | 0.068 | 0.795 | | | 0.001 | 0.966 | | | 0.153 | 0.696 | | Mastectomy | 214(60.28%) | 141(39.72%) | | | 105(59.32%) | 72(40.68%) | | | 109(61.24%) | 69(38.76%) | | | | Breast-conserving surgery | 15(57.69%) | 11(42.31%) | | | 6(60.00%) | 4(40.00%) | | | 9(56.25%) | 7(43.75%) | | | | Tumor size | | | 6.368 | 0.041 | | | 1.719 | 0.424 | | | 6.800 | 0.033 | | ≤2 cm | 94(61.04%) | 60(38.96%) | | | 33(63.46%) | 19(36.54%) | | | 61(59.80%) | 41(40.20%) | | | | >2 and< 5 cm | 114(63.69%) | 65(36.31%) | | | 66(60.00%) | 44(40.00%) | | | 48(69.57%) | 21(30.43%) | | | | ≥ 5 cm | 21(43.75%) | 27(56.25%) | | | 12(48.00%) | 13(52.00%) | | | 9(39.13%) | 14(60.87%) | | | | Postoperative complications | | | 0.104 | 0.748 | | | 0.057 | 0.812 | | | 0.041 | 0.839 | | No | 220(60.27%) | 145(39.73%) | | | 106(59.55%) | 72(40.45%) | | | 114(60.96%) | 73(39.04%) | | | | Yes | 9(56.25%) | 7(43.75%) | | | 5(55.56%) | 4(44.44%) | | | 4(57.14%) | 3(42.86%) | | | | Postoperative chemotherapy | | | 1.405 | 0.236 | | | 1.738 | 0.187 | | | 0.168 | 0.682 | | No | 89(64.03%) | 50(35.97%) | | | 28(68.29%) | 13(31.71%) | | | 61(62.24%) | 37(37.76%) | | | | Yes | 140(57.85%) | 102(42.15%) | | | 83(56.85%) | 63(43.15%) | | | 57(59.38%) | 39(40.63%) | | | | Postoperative radiotherapy | | | 0.153 | 0.695 | | | 2.635 | 0.105 | | | 1.446 | 0.229 | | No | 49(62.03%) | 30(37.97%) | | | 32(69.57%) | 14(30.43%) | | | 17(51.52%) | 16(48.48%) | | | | Yes | 180(59.60%) | 122(40.40%) | | | 79(56.03%) | 62(43.97%) | | | 101(62.73%) | 60(37.27%) | | | | Postoperative endocrine therapy | | | 0.781 | 0.377 | | | 0.066 | 0.797 | | | 0.945 | 0.331 | | No | 92(57.50%) | 68(42.50%) | | | 49(58.33%) | 35(41.67%) | | | 43(56.58%) | 33(43.42%) | | | | Yes | 137(61.99%) | 84(38.01%) | | | 62(60.19%) | 41(39.81%) | | | 75(63.56%) | 43(36.44%) | | | | Postoperative targeted therapy | | | 1.306 | 0.253 | | | 2.529 | 0.112 | | | 0.364 | 0.546 | | No | 190(61.49%) | 119(38.51%) | | | 106(60.92%) | 68(39.08%) | | | 84(62.22%) | 51(37.78%) | | | | Yes | 39(54.17%) | 33(45.83%) | | | 5(38.46%) | 8(61.54%) | | | 34(57.63%) | 25(42.37%) | | |
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#BMI: body mass index.
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