Controlling Nutritional Status (CONUT) as a Novel Postoperative Prognostic Marker in Breast Cancer Patients: A Retrospective Study

Table 3

The relationships between the CONUT score and blood parameters of BC patients.

Parameters	All patients ()			value	Control group ()			value	Treatment group ()			value
Cases ()	LOW 229	HIGH 152			Low 111	High 76			Low 118	High 76
ALB (g/L)			0.252	0.615			0.266	0.606			0.081	0.776
< 44.10	116(61.38%)	73(38.62%)			67(60.91%)	43(39.09%)			49(62.03%)	30(37.97%)
≥ 44.10	113(58.85%)	79(41.15%)			44(57.14%)	33(42.86%)			69(60.00%)	46(40.00%)
TC (mmol/L)			4.555	0.033			0.996	0.318			3.946	0.047
< 4.38	104(54.74%)	86(45.26%)			59(56.19%)	46(43.81%)			45(52.94%)	40(47.06%)
≥ 4.38	125(65.45%)	66(34.55%)			52(63.41%)	30(36.59%)			73(66.97%)	36(33.03%)
TP(g/L)			0.044	0.837			0.200	0.655			0.008	0.927
< 71.90	112(59.57%)	76(40.43%)			46(57.50%)	34(42.50%)			66(61.11%)	42(38.89%)
≥ 71.90	117(60.62%)	76(39.38%)			65(60.75%)	42(39.25%)			52(60.47%)	34(39.53%)
PALB (mg/dl)			1.276	0.259			2.834	0.092			0.006	0.939
< 24	101(57.06%)	76(42.94%)			46(52.87%)	41(47.13%)			55(61.11%)	35(38.89%)
≥ 24	128(62.75%)	76(36.32%)			65(65.00%)	35(35.00%)			63(60.58%)	41(43.62%)
CA125 (U/mL)			2.025	0.155			0.857	0.355			1.345	0.246
< 13.70	121(63.68%)	69(36.32%)			66(62.26%)	40(37.74%)			55(65.48%)	29(34.52%)
≥ 13.70	108(56.54%)	83(43.46%)			45(55.56%)	36(44.44%)			63(57.27%)	47(42.73%)
CA153 (U/mL)			4.205	0.041			1.967	0.161			2.467	0.116
< 12.69	124(65.26%)	66(34.74%)			67(63.81%)	38(36.19%)			57(67.06%)	28(32.94%)
≥ 12.69	105(54.97%)	86(45.03%)			44(53.66%)	38(46.34%)			61(55.96%)	48(44.04%)
CEA (ng/mL)			0.002	0.097			0.171	0.679			0.224	0.636
< 1.86	114(60.00%)	76(40.00%)			56(60.87%)	36(39.13%)			58(59.18%)	40(40.82%)
≥ 1.86	115(60.21%)	76(39.79%)			55(57.89%)	40(42.11%)			60(62.50%)	36(37.50%)
Before chemotherapy
White blood cell (W) (×10^9/L)			32.391	<0.0001			7.831	0.005			27.533	<0.0001
< 5.92	87(45.79%)	103(54.21%)			53(50.48%)	52(49.52%)			34(40.00%)	51(60.00%)
≥ 5.92	142(74.35%)	49(25.65%)			58(70.73%)	24(29.27%)			84(77.06%)	25(22.94%)
Hemoglobin (Hb) (×10^9/L)			4.589	0.032			3.433	0.064			1.510	0.219
< 131	92(54.12%)	78(45.88%)			39(51.32%)	37(48.68%)			53(56.38%)	41(43.62%)
≥ 131	137(64.93%)	74(35.07%)			72(64.86%)	39(35.14%)			65(65.00%)	35(35.00%)
Neutrophil (N) (×10^9/L)			2.528	0.112			0.072	0.788			3.736	0.053
< 3.41	106(56.08%)	83(43.92%)			65(58.56%)	46(41.44%)			41(52.56%)	37(47.44%)
≥ 3.41	123(64.06%)	69(35.94%)			46(60.53%)	30(39.47%)			77(66.38%)	39(33.62%)
Lymphocyte (TLC) (×10^9/L)			107.713	<0.0001			34.847	<0.0001			79.147	<0.0001
< 1.87	64(33.86%)	125(66.14%)			29(35.37%)	53(64.63%)			35(32.71%)	72(67.29%)
≥ 1.87	165(85.94%)	27(14.06%)			82(78.10%)	23(21.90%)			83(95.40%)	4(4.60%)
Monocyte (M) (×10^9/L)			12.091	0.001			3.227	0.072			10.506	0.001
< 0.34	91(50.84%)	88(49.16%)			63(54.31%)	53(45.69%)			28(44.44%)	35(55.56%)
≥ 0.34	138(68.32%)	64(31.68%)			48(67.61%)	23(32.39%)			90(68.70%)	41(31.30%)
Eosinophils (E) (×10^9/L)			5.890	0.015			1.635	0.201			4.876	0.027
< 0.08	102(53.97%)	87(46.03%)			45(54.22%)	38(45.78%)			57(53.77%)	49(46.23%)
≥ 0.08	127(66.15%)	65(33.85%)			66(63.46%)	38(36.54%)			61(69.32%)	27(30.68%)
Basophils (B) (×10^9/L)			4.042	0.044			0.200	0.655			5.751	0.016
< 0.02	79(53.74%)	68(46.26%)			46(57.50%)	34(42.50%)			33(49.25%)	34(50.75%)
≥ 0.02	150(64.10%)	84(35.90%)			65(60.75%)	42(39.25%)			85(66.93%)	42(33.07%)
Platelet (P) (×10^9/L)			4.555	0.033			2.014	0.156			2.469	0.116
< 235	104(54.74%)	86(45.26%)			60(55.05%)	49(44.95%)			44(54.32%)	37(45.68%)
≥ 235	125(65.45%)	66(34.55%)			51(65.38%)	27(34.62%)			74(65.49%)	39(34.51%)
NLR			0.567	0.451			2.040	0.153			0.128	0.720
< 1.82	110(58.20%)	79(41.80%)			51(54.26%)	43(45.74%)			59(62.11%)	36(37.89%)
≥ 1.82	119(61.98%)	73(38.02%)			60(64.52%)	33(35.48%)			59(59.60%)	40(40.40%)
MLR			21.973	<0.0001			6.701	0.010			19.511	<0.0001
< 0.19	136(71.96%)	53(28.04%)			79(66.39%)	40(33.61%)			57(81.43%)	13(18.57%)
≥ 0.19	93(48.44%)	99(51.56%)			32(46.38%)	36(52.17%)			61(49.59%)	63(51.22%)
PLR			39.931	<0.0001			13.612	<0.0001			31.881	<0.0001
< 126.50	145(75.92%)	46(24.08%)			82(69.49%)	36(30.51%)			63(86.30%)	10(13.70%)
≥ 126.50	84(44.21%)	106(55.79%)			29(42.03%)	40(57.97%)			55(45.45%)	66(54.55%)
SIRI			4.562	0.033			1.917	0.166			3.934	0.047
< 0.64	122(65.59%)	64(34.41%)			78(62.90%)	46(37.10%)			44(70.97%)	18(29.03%)
≥ 0.64	107(54.87%)	88(45.13%)			33(52.38%)	30(47.62%)			74(56.06%)	58(43.94%)
SII			11.490	0.001			5.400	0.020			7.409	0.006
< 434.20	131(68.59%)	60(31.41%)			77(65.81%)	40(34.19%)			54(72.97%)	20(27.03%)
≥ 434.20	98(51.58%)	92(48.42%)			34(48.57%)	36(51.43%)			64(53.33%)	56(46.67%)
PNI			38.360	<0.0001			10.310	0.001			30.555	<0.0001
< 53.50	84(44.44%)	105(55.56%)			48(48.48%)	51(51.52%)			36(40.00%)	54(60.00%)
≥ 53.50	145(75.52%)	47(24.48%)			63(71.59%)	25(28.41%)			82(78.85%)	22(21.15%)

^#ALB: serum albumin concentration; TC: total serum cholesterol; TP: total protein; PALB: prealbumin; NLR = Neutrophil/Lymphocyte ratio; MLR = Monocyte/Lymphocyte ratio; PLR = Platelet/Lymphocyte ratio; SIRI (Systemic inflammation response index) = neutrophil (N) × monocyte (M)/lymphocyte (TLC); SII (Systemic Immune–inflammation Index) = (neutrophil (N) × platelet (P))/lymphocyte (TLC); .