Antiproliferative Activity of Two Unusual Dimeric Flavonoids, Brachydin E and Brachydin F, Isolated from Fridericia platyphylla (Cham.) L.G.Lohmann: In Vitro and Molecular Docking Evaluation

Figure 3

Photomicrographs of PC-3 cells at 0 h (a, c, i, k) and after 48 h treatment with DMSO (b, j), Brachydin E (d), and Brachydin F (l). Percentage of wound closure for PC-3 cells over the treatment period (24 h and 48 h) with DMSO, Brachydin E, and Brachydin F, respectively (e, m). Photographs of PC-3 colonies treated with DMSO (f, n), Brachydin E (g), and Brachydin F (o) after 21 days. Number of PC-3 colonies formed after 21 days of treatment with DMSO, Brachydin E, and Brachydin F, respectively (h, p). ; ((e, m) ANOVA, Tukey test; (h, p) -test).

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