Antiproliferative Activity of Two Unusual Dimeric Flavonoids, Brachydin E and Brachydin F, Isolated from Fridericia platyphylla (Cham.) L.G.Lohmann: In Vitro and Molecular Docking Evaluation

Table 3

Physico-chemical and ADME parameters predicted for Brachydins E and F.

Parameter	Brachydin E	Brachydin F
Hydrogen-bond acceptors (HBA)	16	17
Hydrogen-bond donors (HBD)	8	8
LogP	3.02	2.61
TPSA	251.36 A2	268.43 A2
Gastrointestinal absorption	Low	Low
Blood-brain barrier permeant	No	No
Metabolism enzyme inhibitors	0	0