Propylene Glycol Caprylate-Based Nanoemulsion Formulation of Plumbagin: Development and Characterization of Anticancer Activity

Figure 6

In vitro antiproliferative activity of plumbagin-loaded nanoemulsion. Effect of free plumbagin (PLBG), plumbagin-loaded nanoemulsion (NE-PL, 4.7% ), and control empty nanoemulsions (NE-C) on cell viability of PTEN-P2 cells was determined in a dose-dependent manner. For control drug-free nanoemulsion, NE-C, the cells were exposed to the same concentration of nanoemulsion without plumbagin. PTEN-P2 cells were incubated with increasing dilutions of formulations for 24 h, and then, % cell viability was determined using cell proliferation assay (MTS).