A Famous Chinese Medicine Formula: Yinhuo Decoction Antagonizes the Damage of Corticosterone to PC12 Cells and Improves Depression by Regulating the SIRT1/PGC-1<i>α</i> Pathway

<div>Yinhuo Decoction reduced the levels of CORT, total GCR in the brain, GCR in the hippocampus DG, and GCR in the hypothalamus. (a) Total CORT level in the brain was detected via using ELISA. (b) The GCR protein level in the whole brain was detected by western blot. (c and d) The GCR protein level in hippocampus DG was detected by IHC. (e–f) GCR protein level in hypothalamus was detected by IHC. <span class="nowrap"><svg height="12.7112pt" id="M16" style="vertical-align:-3.403299pt" version="1.1" viewbox="-0.0498162 -9.3079 113.045 12.7112" width="113.045pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.013,0,0,-0.013,0,0)"><path d="M861 0V28C774 35 771 41 768 147L759 509C756 612 762 614 851 622V650H681L449 149L221 650H57V622C148 613 153 609 144 479L130 271C123 166 117 123 111 88C104 46 85 34 26 28V0H259V28C192 35 169 42 167 90C166 130 166 173 170 256L185 541H187L411 7H431L675 555H679L683 147C683 41 680 35 598 28V0H861Z"></path></g><g transform="matrix(.013,0,0,-0.013,11.361,0)"><path d="M433 39L423 65C413 59 399 54 387 54C370 54 352 69 352 114V299C352 352 342 392 307 422C285 440 255 449 225 449C168 437 102 399 75 379C56 365 44 353 44 339C44 315 69 296 87 296C101 296 111 303 116 319C124 349 133 371 145 385C156 397 171 404 190 404C241 404 275 364 275 291V274C253 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BioMed Research International

fig3

Figure 3

Figure 3: A Famous Chinese Medicine Formula: Yinhuo Decoction Antagonizes the Damage of Corticosterone to PC12 Cells and Improves Depression by Regulating the SIRT1/PGC-1<i>α</i> Pathway 

Figure 3 | A Famous Chinese Medicine Formula: Yinhuo Decoction Antagonizes the Damage of Corticosterone to PC12 Cells and Improves Depression by Regulating the SIRT1/PGC-1α Pathway 