A Famous Chinese Medicine Formula: Yinhuo Decoction Antagonizes the Damage of Corticosterone to PC12 Cells and Improves Depression by Regulating the SIRT1/PGC-1α Pathway

Figure 4

Yinhuo Decoction reduced the damage of PC12 cells induced by CORT. (a) After treatment with different concentration of CORT for 6 h, MTT was conducted to detect PC12 cells viability. (b) After treatment with different concentration of CORT for 12 h, MTT was conducted to detect PC12 cells viability. (c) After treatment with different concentration of CORT for 24 h, MTT was conducted to detect PC12 cells viability. (d) After treatment with different concentration of CORT for 48 h, MTT was conducted to detect PC12 cells viability. (e) Cell activity was measured at 24 h after the PC12 were treated with different concentrations of Yinhuo Decoction. (f) After corresponding treatment, PC12 cell activity was measured by MTT. , or , or indicated vs. Control group; indicated vs. Model group.

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