Review Article

Diagnostic and Prognostic Roles of Thrombospondin-2 in Digestive System Cancers

Table 2

Characteristics of included studies related to prognosis.

First authorYearJournalLocationDiseaseSample sizeSampleOS HR (95% CI)DFS HR (95% CI)NOS

Peng [37]2018Annals of Surgical OncologyChinaPancreatic cancer263Blood1.822 (1.389-2.389)6
Lin [28]2015American Journal of Translational ResearchChinaRectal cancer172Tissue0.327 (0.160-0.670)7
Tian [39]2018Official Journal of the Balkan Union of OncologyChinaColorectal cancer100Tissue4.219 (1.795-9.901)6
Zhang [27]2017British Journal of CancerChinaHepatocellular carcinoma44Blood2.070 (0.896-4.779)2.69 (1.203-6.012)6
Liu [11]2020Molecular Cancer TherapeuticsUSAColorectal cancer149Blood1.49 (1.22-1.83)7
Fei [10]2017OncotargetChinaColorectal cancer402Blood1.261 (0.776-2.05)6
Byrling [40]2020Journal of Translational MedicineEuropeCholangiocarcinoma59Tissue3.34 (0.94-11.8)3.95 (1.09-14.3)9
Nixon [41]2013Clinical Cancer ResearchUSAPancreatic cancer159Blood1.6 (1.1-2.1)7
Sun [29]2014Molecular CancerChinaGastric cancer129Tissue0.51 (0.31-0.85)8
Liu [42]2015Molecular Cancer TherapeuticsUSAColorectal cancer49Blood2.9 (1.44-5.04)5

NOS: Newcastle-Ottawa scale; OS: overall survival; DFS: disease-free survival.