Diagnostic and Prognostic Roles of Thrombospondin-2 in Digestive System Cancers

Table 4

Subgroup analysis of overall survival.

	Number of studies	HR (95% CI)	Heterogeneity
			(%)
Sample size
≤140	4	2.96 (1.97-4.46)	0.0	0.705
>140	4	1.57 (1.37-1.80)	0.0	0.530
Location
Europe and America	4	1.61 (1.37-1.90)	42.7	0.155
Asia	4	1.80 (1.45-2.25)	50.0	0.112
Published year
≤2015	2	1.81 (1.36-2.42)	63.5	0.098
>2015	6	1.64 (1.42-1.90)	43.1	0.118
Sample
Blood	6	1.63 (1.42-1.86)	17.4	0.301
Tissue	2	3.92 (1.93-7.96)	0.0	0.764
Disease
Pancreatic cancer	2	1.73 (1.40-2.13)	0.0	0.546
Colorectal cancer	4	1.61 (1.35-1.91)	69.4	0.020
Hepatobiliary cancer	2	2.40 (1.19-4.81)	0.0	0.537