Upregulation of Centromere Proteins as Potential Biomarkers for Esophageal Squamous Cell Carcinoma Diagnosis and Prognosis

Figure 1

Aberrant expression of CENPs in ESCC. (a–c) Heatmaps showing expression differences of CENP-encoding genes between the tumor and normal samples in order of descending logFC in TCGA, GSE38129, and GSE20347. Blue and red colors represent low and high expression, respectively. ; ; ; and ^NS. Genes with and were identified as DEGs. (d) Venn diagram displaying the overlapped DEGs in the three datasets, including CENPA, E, F, I, M, N, Q, and R. (e–g) Boxplots representing the different expression levels of the overlapped genes in tumor and normal samples according to TCGA, GSE38129, and GSE20347.

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