Research Article

Utilization of HCV Viremic Kidneys with Genotyping/Subtyping-Free Sofosbuvir/Velpatasvir Treatment Strategy: Experience from China

Table 2

Characteristics and outcomes of recipients.

All ()D+/R- ()D+/R+ () value

Age, yr, mean (SD)0.082
Weight, kg, mean (SD)0.535
Gender, male, (%)17 (73.9)10 (71.4)7 (77.8)1.000
Cause of ESRD, (%)0.815
 Glomerulonephritis19 (82.6)12 (85.7)7 (77.8)
 Hypertension2 (8.7)1 (7.1)1 (11.1)
 Polycystic kidney disease1 (4.3)1 (7.1)0
 Diabetes mellitus1 (4.3)01 (11.1)
Blood type, (%)0.360
 B8 (34.8)5 (35.7)3 (33.3)
 A7 (30.4)3 (21.4)4 (44.4)
 AB4 (17.4)4 (28.6)0
 O4 (17.4)2 (14.3)2 (22.2)
Dialysis time, mon, median (IQR)18 (10-31)16.5 (8.7-28.7)18 (10.5-40)0.654
Prior transplant, yes, (%)1 (4.3)1(7.1)01.000
HLA mismatch, mean (SD)0.183
APRI (pretransplantation)0.059
Induction immunosuppression (, %)
 Basiliximab7 (0.30)3 (21.4)4 (44.4)0.242
 ATG14 (0.61)10 (71.4)4 (44.4)0.196
 No-use2 (0.09)1 (7.1)1 (11.1)0.742
SVR12100%100%100%0.801
HCV viral load at treatment start (log 10 IU/mL), median (IQR)4.26 (2.90-5.90)3.61 (2.57-4.57)5.98 (5.28-6.53)0.002
Abnormal liver year, (%)5 (21.7)1 (7.1)4 (44.4)0.056
ALT at 3-month posttransplant, mean (SD)0.298
ALT at 6-month posttransplant, mean (SD)0.801
Delayed graft function, (%)9 (39.1)6 (42.9)3 (33.3)1.000
Acute year, (%)3 (13.0)2 (14.3)1 (11.1)1.000
eGFR at 3-month posttransplant, mean (SD)0.746
eGFR at 6-month posttransplant, mean (SD)0.798
1-year death-censored graft survival100%100%100%
1-year patient survival100%100%100%

ESRD: end-stage kidney disease; HLA: human leukocyte antigen; eGFR: estimated glomerular filtration rate; APRI: aspartate aminotransferase-to-platelet ratio index; ATG: anti-human T lymphocyte rabbit immunoglobulin.