Research Article

Radix Salvia miltiorrhiza for Ankylosing Spondylitis: Determining Potential Inflammatory Molecular Targets and Mechanism Using Network Pharmacology

Figure 8

Effects of cryptotanshinone and tanshinone IIA on PTGS2, IL-6, and TNF-α protein expression. (a) Visual protein expression levels in peripheral blood mononuclear cells from the healthy control group (HC), nontreatment group (NT), AS+cryptotanshinone group (AS+cryptotanshinone), and AS+tanshinone IIA group (AS+tanshinone IIA). (b) Quantitative expression of PTGS2 (COX2) in each group. (c) Quantitative expression of IL-6 in each group. (d) Quantitative expression of TNF-α in each group. Data are represented as . and , compared with the normal control group. # and ##, compared with the NT group. The experiments were independently repeated at least three times.
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