Radix Salvia miltiorrhiza for Ankylosing Spondylitis: Determining Potential Inflammatory Molecular Targets and Mechanism Using Network Pharmacology

Table 1

Changes in immune-inflammatory indices after treatment with RSM ().

	Before treatment	After treatment	value
ESR [median (Q1, Q3), mm/h]	28.00 (14.00, 49.00)	21.00 (12.00, 37.00)	≤0.001	-16.986
CRP [median (Q1, Q3), mg/L]	18.215 (5.44, 38.70)	8.025 (1.90, 21.2125)	≤0.001	-21.266
IgA [median (Q1, Q3), g/L]	2.59 (1.87, 3.51)	2.44 (1.81, 3.305)	≤0.001	-10.594
IgM [median (Q1, Q3), g/L]	1.13 (0.825, 1.48)	1.13 (0.84, 1.50)	0.359	-.916
IgG [median (Q1, Q3), g/L]	13.07 (10.68, 15.80)	12.51 (10.30, 15.00)	≤0.001	-9.013
C3 [median (Q1, Q3), g/L]	120.50 (81.20, 139.50)	111.50 (75.95, 129.80)	≤0.001	-11.391
C4 [median (Q1, Q3), g/L]	28.50 (16.25, 35.80)	24.60 (14.15, 31.05)	≤0.001	-16.504

Note: ESR: Erythrocyte sedimentation rate; CRP: C-reactive protein; IgA: immunoglobulin A; IgM: immunoglobulin M; IgG: immunoglobulin G; C3: complement component 3; C4: complement component 4. value is based on the comparison between levels before and after treatment. is the standardized test statistics before and after treatment.