Association between XRCC3 rs861539 Polymorphism and the Risk of Ovarian Cancer: Meta-Analysis and Trial Sequential Analysis

Table 1

Main characteristics of the studies included in the meta-analysis.

First author	Year	Country	Ethnicity	Cases/controls	Cases			Controls			HWE	Quality score
					GG	GA	AA	GG	GA	AA
Kumar	2021	India	Caucasian	200/200	136	49	15	140	51	9	0.131	7
Smolarz	2019	Poland	Caucasian	600/600	147	307	146	117	317	166	0.118	8
Mackawy	2019	Egypt	Caucasian	50/20	21	17	12	14	4	2	0.094	7
Michalska	2016	Poland	Caucasian	700/700	180	340	180	150	350	200	0.892	8
Gao	2015	China	Asian	70/70	62	6	2	60	10	0	0.520	8
Monteiro	2014	Brazil	Mixed	70/70	32	33	5	32	33	5	0.368	8
Beesley	2007	Australia	Caucasian	731/747	291	339	101	288	351	108	0.950	7
Webb	2005	Australia	Caucasian	543/1125	229	238	76	438	538	149	0.420	8
Auranen1	2005	UK	Caucasian	749/830	297	347	105	318	404	108	0.248	7
Auranen2	2005	US	Caucasian	270/344	125	114	31	130	174	40	0.111	7
Auranen3	2005	Denmark	Caucasian	361/891	144	168	49	358	394	139	0.080	7
Auranen4	2005	UK	Caucasian	290/1784	130	121	39	728	827	229	0.806	7