The Impact of a History of Different Other Cancers on the Long-Term Outcomes of Patients with Intrahepatic Cholangiocarcinoma: A Population-Based Analysis
Table 3
Multivariate Cox regression analysis of OS and CSS in ICC patients stratified by initial prior cancer site.
Characteristics
OS
CSS
HR (95% CI)
HR (95% CI)
Prior cancer site (vs. <none)
Breast
0.797 (0.630-1.008)
0.059
0.748 (0.574-0.975)
0.032
Colon and rectum
0.886 (0.791-1.120)
0.312
0.856 (0.640-1.145)
0.294
Prostate
0.865 (0.729-1.027)
0.098
0.786 (0.649-0.953)
0.014
Bladder
1.298 (0.949-1.774)
0.102
1.204 (0.849-1.708)
0.297
Liver/gallbladder/other bile duct
0.870 (0.611-1.240)
0.442
0.829 (0.567-1.210)
0.331
Oral cavity and pharynx
0.809 (0.537-1.219)
0.311
0.737 (0.469-1.157)
0.185
Melanoma
1.021 (0.732-1.424)
0.903
0.900 (0.621-1.306)
0.581
Uteri
0.864 (0.583-1.281)
0.468
0.903 (0.568-1.437)
0.668
Non-Hodgkin lymphoma
0.728 (0.491-1.080)
0.115
0.737 (0.469-1.157)
0.185
Kidney
1.438 (0.936-2.209)
0.097
1.476 (0.889-2.452)
0.133
Note: ICC: intrahepatic cholangiocarcinoma; HR: hazard ratio; CI: confidence interval; OS: overall survival; CSS: cancer specific survival.