Research Article

The Impact of a History of Different Other Cancers on the Long-Term Outcomes of Patients with Intrahepatic Cholangiocarcinoma: A Population-Based Analysis

Table 3

Multivariate Cox regression analysis of OS and CSS in ICC patients stratified by initial prior cancer site.

CharacteristicsOSCSS
HR (95% CI)HR (95% CI)

Prior cancer site (vs. <none)
Breast0.797 (0.630-1.008)0.0590.748 (0.574-0.975)0.032
Colon and rectum0.886 (0.791-1.120)0.3120.856 (0.640-1.145)0.294
Prostate0.865 (0.729-1.027)0.0980.786 (0.649-0.953)0.014
Bladder1.298 (0.949-1.774)0.1021.204 (0.849-1.708)0.297
Liver/gallbladder/other bile duct0.870 (0.611-1.240)0.4420.829 (0.567-1.210)0.331
Oral cavity and pharynx0.809 (0.537-1.219)0.3110.737 (0.469-1.157)0.185
Melanoma1.021 (0.732-1.424)0.9030.900 (0.621-1.306)0.581
Uteri0.864 (0.583-1.281)0.4680.903 (0.568-1.437)0.668
Non-Hodgkin lymphoma0.728 (0.491-1.080)0.1150.737 (0.469-1.157)0.185
Kidney1.438 (0.936-2.209)0.0971.476 (0.889-2.452)0.133

Note: ICC: intrahepatic cholangiocarcinoma; HR: hazard ratio; CI: confidence interval; OS: overall survival; CSS: cancer specific survival.