Study on the Anticancer Activity of Prodigiosin from Variants of Serratia Marcescens QBN VTCC 910026

Figure 5

The effect of Pg on tumor in the thigh of mice before and after treatment. (a). The effect of Pg on tumor growth of mice after 28 days. Control: Healthy mice. Capecitabine: Mice were orally administrated with capecitabine at the dose of 200 mg/kg/day. PG: Mice were received with Pg at the dose of 2 mg/kg/day. Significance was determined using an unpaired two tailed t test: p <0.0001, p <0.001, p <0.005, p <0.05. Ns: Non-significant. Each value is expressed as mean ± SD. n = 10 per group. The average of tumor weight of all mice. (b). Tumor from mice without drug treatment. (c). Tumor was from mice orally administrated with capecitabine at the dose of 200 mg/kg. (d). Tumor was from mice injecting with Pg at the dose of 1 mg/kg (e).

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