[Retracted] HDAC3 Inhibition Alleviates High-Glucose-Induced Retinal Ganglion Cell Death through Inhibiting Inflammasome Activation

Figure 5

HDAC3 inhibition alleviated inflammation in HG-treated RGCs through inhibiting inflammasome activation. (a) The COX-2 contents in normal, HG, and HG+RGFP966 cotreatment RGC groups. (b) The IL-6 contents in normal, HG, and HG+RGFP966 cotreatment RGC groups. (c) The MCP-1 contents in normal, HG, and HG+RGFP966 cotreatment RGC groups. (d) The TNF-α contents in normal, HG, and HG+RGFP966 cotreatment RGC groups. (e) The inflammasome-related NLRP3, ASC, IL-1β, and IL-18 in normal, HG, and HG+RGFP966 cotreatment, HG+RGFP966+NLRP3 overexpression cotreatment, and HG+RGFP966+control vector RGC groups. , based on Student’s -test.

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