[Retracted] HDAC3 Inhibition Alleviates High-Glucose-Induced Retinal Ganglion Cell Death through Inhibiting Inflammasome Activation

Figure 6

Scientific diagram of the effects of HDAC3 inhibition on HG-treated RGCs. HDAC3 was upregulated in HG-treated RGCs, and thus, HDAC3 inhibition would promote cell viability, inhibit apoptosis, alleviate inflammation, and moderate oxidative stress. NLRP3 inflammasome activation played a key role in neurodegeneration in DR, and it could be blocked by HDAC3 inhibition.