Research Article

[Retracted] Activating IL-6/STAT3 Enhances Protein Stability of Proteasome 20S α+β in Colorectal Cancer by miR-1254

Table 2

Correlation between proteasome 20S α+β expression and clinicopathologic characteristics in 90 CRC patients.

VariablesProteasome 20S α+β expression
TotalLowHigh value

Gender0.432
 Male4232 (76.2%)10 (23.8%)
 Female4833 (68.8%)15 (31.2%)
Age (years)0.595
 ≤602922 (75.9%)7 (24.1%)
 >606143 (70.5%)18 (29.5%)
Size0.001
 ≤5 cm4338 (88.4%)5 (11.6%)
 >5 cm4727 (57.4%)20 (42.6%)
Depth of invasion0.457
 ≤pT21311 (84.6%)2 (15.4%)
 ≥pT37754 (70.1%)23 (29.9%)
Lymph node metastasis0.002
 No5949 (83.1%)10 (16.9%)
 Yes3116 (51.6%)15 (48.4%)
Distant metastasis0.030
 No metastasis8564 (75.3%)21 (24.7%)
 Metastasis51 (20.0%)4 (80.0%)
Localization0.367
 Proximal colon1412 (85.7%)2 (14.3%)
 Distal colon7653 (69.7%)23 (30.3%)
TNM stage≤0.01
 I and II5749 (86.0%)8 (14.0%)
 III and IV3316 (48.5%)17 (51.5%)
Histological grade0.140
 Well65 (83.3%)1 (16.7%)
 Moderately7053 (75.7%)17 (24.3%)
 Poorly147 (50.0%)7 (50.0%)
CEA (μg/L)≤0.01
 ≥55447 (87.0%)7 (13.0%)
 <53618 (72.2%)18 (27.8%)
pSTAT3≤0.01
 Low5751 (89.47%)6 (10.53%)
 High3314 (42.42%)19 (57.58%)

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