Research Article
[Retracted] Activating IL-6/STAT3 Enhances Protein Stability of Proteasome 20S α+β in Colorectal Cancer by miR-1254
Table 2
Correlation between proteasome 20S α+β expression and clinicopathologic characteristics in 90 CRC patients.
| Variables | Proteasome 20S α+β expression | Total | Low | High | value |
| Gender | | | | 0.432 | Male | 42 | 32 (76.2%) | 10 (23.8%) | | Female | 48 | 33 (68.8%) | 15 (31.2%) | | Age (years) | | | | 0.595 | ≤60 | 29 | 22 (75.9%) | 7 (24.1%) | | >60 | 61 | 43 (70.5%) | 18 (29.5%) | | Size | | | | 0.001 | ≤5 cm | 43 | 38 (88.4%) | 5 (11.6%) | | >5 cm | 47 | 27 (57.4%) | 20 (42.6%) | | Depth of invasion | | | | 0.457 | ≤pT2 | 13 | 11 (84.6%) | 2 (15.4%) | | ≥pT3 | 77 | 54 (70.1%) | 23 (29.9%) | | Lymph node metastasis | | | | 0.002 | No | 59 | 49 (83.1%) | 10 (16.9%) | | Yes | 31 | 16 (51.6%) | 15 (48.4%) | | Distant metastasis | | | | 0.030 | No metastasis | 85 | 64 (75.3%) | 21 (24.7%) | | Metastasis | 5 | 1 (20.0%) | 4 (80.0%) | | Localization | | | | 0.367 | Proximal colon | 14 | 12 (85.7%) | 2 (14.3%) | | Distal colon | 76 | 53 (69.7%) | 23 (30.3%) | | TNM stage | | | | ≤0.01 | I and II | 57 | 49 (86.0%) | 8 (14.0%) | | III and IV | 33 | 16 (48.5%) | 17 (51.5%) | | Histological grade | | | | 0.140 | Well | 6 | 5 (83.3%) | 1 (16.7%) | | Moderately | 70 | 53 (75.7%) | 17 (24.3%) | | Poorly | 14 | 7 (50.0%) | 7 (50.0%) | | CEA (μg/L) | | | | ≤0.01 | ≥5 | 54 | 47 (87.0%) | 7 (13.0%) | | <5 | 36 | 18 (72.2%) | 18 (27.8%) | | pSTAT3 | | | | ≤0.01 | Low | 57 | 51 (89.47%) | 6 (10.53%) | | High | 33 | 14 (42.42%) | 19 (57.58%) | |
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