[Retracted] Activating IL-6/STAT3 Enhances Protein Stability of Proteasome 20S α+β in Colorectal Cancer by miR-1254

Table 3

Univariate and multivariate Cox regression analyses of overall survival in 90 CRC patients.

Variables	Univariate analysis (Cox: enter)			Multivariate analysis (Cox: forward conditional)
	HR	95% CI	p	HR	95% CI
Gender
Male versus female	0.770	0.389–1.526	0.454
Age (years)
≤60 versus >60	1.200	0.574–2.511	0.628
Size (cm)
≤5 versus >5	3.471	1.616–7.456	0.001
Depth of invasion
≤pT2 versus ≥pT3	1.945	0.594–6.365	0.271
Lymph node metastasis
No versus yes	3.197	1.619–6.310	0.001
Distant metastasis
No metastasis versus metastasis	2.841	0.996–8.105	0.051
Localization
Proximal versus distal	1.131	0.438–2.922	0.799
Histological grade
Well and moderate versus poor	2.824	1.385–5.760	0.004
TNM stage
I and II versus III and IV	3.866	1.927–7.758	≤0.01	2.423	1.093–5.376	0.029
CEA
≥5 versus <5	1.081	0.546–2.141	0.823
pSTAT3
Low versus high	2.762	1.397–5.458	0.003
Proteasome 20S α+β
Low versus high	5.335	2.679–10.624	≤0.01	4.214	2.058–8.628	≤0.01

HR: hazard ratio; 95% CI: 95% confidence interval.