Preventive Effect of Hippocampal Sparing on Cognitive Dysfunction of Patients Undergoing Whole-Brain Radiotherapy and Imaging Assessment of Hippocampal Volume Changes

Figure 1

Hippocampal contouring atlas. Note: (a) beginning level (beginning of the most inferior pole of the hippocampus). The gray matter areas medial to the lateral ventricles were delineated starting at the emergence of the inferior horn of the lateral ventricle, and the white matter areas were not delineated. (b) The delineation of the gray matter area in the inferior horn of the lateral ventricle. (c) The posterior hyphae (white matter area) was omitted. (d) As the level moved up, the hippocampus gradually moved posteriorly, omitting the posteriorly located germinal hairs and the anteriorly located amygdala. (e) The anteriorly located amygdala and hook-shaped echo. (f) The uncal recess in the inferior horn of the lateral ventricle appeared, behind which was the hippocampus. The medial margin of the hippocampus does not exceed the vertical line of the uncal recess. (g) The delineation was continued upward. The gray matter area anterior to the germinal hairs and the inferior horn of the lateral ventricle was omitted from delineation. (h) The fourth ventricle appeared, and the medial border of the hippocampus was bordered by the fourth ventricle. (i) The inferior horn of the lateral ventricle started to become blurred, and the medial border of the hippocampus was bordered by the fourth ventricle. (j) The fourth ventricle as the boundary. (k) The fourth ventricle as the boundary. (l) The fourth ventricle as the boundary. (m) The fourth ventricle as the boundary. (n) The caudal part of the hippocampus was located posterior to the thalamus and curved toward the uncal recess. (o) The caudal part of the hippocampus extended posteriorly to the anteromedial side of the lateral ventricles. (p) The caudal part of the hippocampus extended posteriorly to the anteromedial side of the lateral ventricles. (q) The caudal part of the hippocampus remained at the lateral border of the fourth ventricle during the continuous upward scanning. (r) The display of the caudal part of the hippocampus terminated in the appearance of white matter between the lateral ventricles and the gray matter of the hippocampus.

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