Tex264 Binding to SNX27 Regulates Itgα5 Receptor Membrane Recycling and Affects Cell Migration

Figure 5

TEX264 knockdown affects SNX27 cell localization and inhibits membrane localization of Itgα5 integrin receptors. (a) HeLa cells were transfected with siTEX264 or scramble siRNA and stained with an antibody against SNX27 24 h later. Scale bar, 20 μm. (b) HeLa cells transfected with siTEX264 or scramble siRNA. After 48 h, cells were live-stained with an antibody against Itgα5 48 h after transfection to reveal surface levels of the Itgα5 integrin receptor. Scale bar, 20 μm.

(a)

(b)