Identification of Inflammation-Related Genes and Exploration of Regulatory Mechanisms in Patients with Osteonecrosis of the Femoral Head

Figure 6

Validation and efficacy evaluation of the 4 hub genes. (a) The 4 hub genes exhibited higher expression levels in SONFH than controls in GSE123568. (b) ROC curves of the 4 hub genes showed high sensitivity and specificity for SONFH diagnosis. (c–f) Results qRT-PCR showed that the relative expressions of CD14, CYBB, NOD2, and TLR1 were also significantly increased in peripheral blood of SONFH patients compared to controls.

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