[Retracted] The Role of 12/15-Lipoxygenase and Its Various Metabolites Generated from Multiple Polyunsaturated Fatty Acids as Substrates in Inflammatory Responses

Figure 2

Metabolic pathway of arachidonic acid. COX is cyclooxygenase. PGs are prostaglandins. CYP450 is cytochrome P450 monooxygenase. EETs are epoxyeicosatrienoic acids. LOX is lipoxygenase. LTs are leukotrienes. 12S-HpETE is 12S-hydroperoxy-eicosatetraenoic acid. PhGPx is phospholipid-hydroperoxide glutathione peroxidase. 12-HETE is 12-hydroxyeicosatetraenoic acid. HXA3 is hepoxilin A3. EH is epoxy hydrolase. TrXA3 is trioxilin A3.