High Expression of E2F4 Is an Adverse Prognostic Factor and Related to Immune Infiltration in Oral Squamous Cell Carcinoma

Table 2

Univariate and multivariate Cox proportional risk regression analyses of E2F4.

Characteristics	Total ()	Univariate analysis		Multivariate analysis
		Hazard ratio (95% CI)	value	Hazard ratio (95% CI)	value
Age	327	1.306 (0.943-1.808)	0.108	1.299 (0.918-1.838)	0.139
≤60	155
>60	172
Gender	328	1.112 (0.793-1.559)	0.540	1.030 (0.719-1.477)	0.871
Male	226
Female	102
Clinical stage	318	1.272 (0.882-1.834)	0.198	1.239 (0.849-1.807)	0.267
Stage I-II	90
Stage III-IV	228
Histologic grade	320	1.264 (0.869-1.837)	0.220	1.214 (0.831-1.773)	0.315
G1-2	251
G3-4	69
E2F4	328	1.405 (1.017-1.941)	0.039	1.384 (0.993-1.929)	0.048
Low	164
High	164